32848-23-0

Upstream product

• 100-02-7 4-nitro-phenol 
• 375-72-4 Nonafluorobutanesulfonyl fluoride 
• 25628-11-9 phenyl 1,1,2,2,3,3,4,4,4-nonafluoro-1-butanesulfonate 
• 375-73-5 perfluorobutanesulfonic acid 

Downstream Products

• 252573-81-2 2,5-dimethylphenyl nonaflate 
• 34859-82-0 l-(tert-butyl)-4-(4-nitrophenoxy)benzene 
• 247018-51-5 4-t-butylphenyl 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonate 
• 199465-44-6 4-iodophenyl nonaflate 
• 93131-74-9 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonic acid 4-methoxyphenyl ester 
• 42096-34-4 naphthalen-2-yl 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonate 
• 52898-51-8 N-methoxy-N-methyl-4-nitrobenzamide 
• 375-72-4 Nonafluorobutanesulfonyl fluoride 

Relevant academic research and scientific papers

METHOD FOR RECOVERING SULFONIC ESTERS OR SULFONYL HALIDES FROM SALTS OF SULFONIC ACIDS

A method for the obtainment of an ester or a halide of a fluorinated sulfonic acid from an salt of a sulfonic acid is herein disclosed. The method is particularly useful for recovering waste sulfonate salts from reaction mixtures obtained by reaction of sulfonic esters of alcohols having a pKa lower than 15 with nucleophile compounds.

A general method for palladium-catalyzed reactions of primary sulfonamides with aryl nonaflates

A general method for Pd-catalyzed sulfonamidation of aryl nonafluorobutanesulfonates (aryl nonaflates) is described. A biaryl phosphine ligand, t-BuXPhos, formed the most active catalyst, and K3PO 4 in tert-amyl alcohol was found to be the optimal base-solvent combination for the reaction. The reaction conditions were tolerant of various functional groups such as cyano, nitro, ester, aldehyde, ketone, chloride, carbamate, and phenol. Heterocyclic aryl nonaflates were found to be suitable coupling partners. High yields of the coupled products were obtained from the reactions between inherently disfavored substrates such as electron-rich nonaflates and electron-poor sulfonamides. Kinetic data suggest reductive elimination to be the rate-limiting step for the reaction. The only limitation of this methodology that we have identified is the inability of 2,6-disubstituted aryl nonaflates to efficiently participate in the reaction.