32916-20-4Relevant academic research and scientific papers
One pot synthesis of trifluoromethyl aryl sulfoxides by trifluoromethylthiolation of arenes and subsequent oxidation with hydrogen peroxide
Horvat, Monika,Iskra, Jernej,Jereb, Marjan,Kodri?, Gregor
, p. 34534 - 34540 (2020/10/12)
Hydrogen peroxide was used for oxidation of various aryl trifluoromethyl sulfides. Trifluoroacetic acid was used as an activating solvent that enables non-catalyzed oxidation and increases selectivity for sulfoxide formation. As shown by oxidation of thianthrene TFA enhances electrophilic character of the oxidant and further oxidation of sulfoxide group is blocked. We have joined trifluoromethylthiolation of arenes using a modified Billard reagent (p-ClPhNHSCF3) with oxidation of aryl trifluoromethyl sulfides using 1.2 equiv. of 30% aqueous hydrogen peroxide and this one-pot process has superior yields than would have been obtained in a two step process.
Electrochemical synthesis of sulfinic esters from alcohols and thiophenols
He, Yang,Zhang, Jinli,Xu, Liang,Wei, Yu
supporting information, (2020/01/31)
Electrochemical oxidative couplings between S[sbnd]H and O[sbnd]H bonds are achieved herein directly from readily-available alcohols and thiophenols, affording a series of diverse sulfinic esters. This strategy can take advantage of 6 equivalents of alcohol, relative to thiophenol, to achieve moderate to good yields, without the assistance of any metallic catalysts, bases, and additional oxidants.
Selective oxidation and chlorination of trifluoromethylsulfide using trichloroisocyanuric acid in ionic liquid
Tang, Ri-Yuan,Zhong, Ping,Lin, Qiu-Lian
, p. 636 - 640 (2008/01/06)
A route to chemoselective oxidation and chlorination of aryltrifluoromethylsulfide using trichloroisocyanuric acid (TCCA) in ionic liquid, an efficiently O-methylation reaction and a reduction of nitro- to amido- in excellent yields have been developed.
