7472-70-0

Basic information

• Product Name: 1,2-dichloro-N,N-bis(4-methylphenyl)ethane-1,2-diimine
• CAS NO: 7472-70-0
• Molecular Formula: C₁₆H₁₄Cl₂N₂
• Molecular Weight: 305.207
• Mol File: 7472-70-0.mol

Chemical Properties

• CAS DataBase Reference: 1,2-dichloro-N,N-bis(4-methylphenyl)ethane-1,2-diimine(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-dichloro-N,N-bis(4-methylphenyl)ethane-1,2-diimine(7472-70-0)
• EPA Substance Registry System: 1,2-dichloro-N,N-bis(4-methylphenyl)ethane-1,2-diimine(7472-70-0)

Safety Data

• Hazardous Substances Data: 7472-70-0(Hazardous Substances Data)

Usage

Type of Compound

Synthetic compound

Use

Antimalarial medication

Mechanism of Action

Interferes with the metabolism of the malaria parasite, preventing its growth and spread in the body

Effectiveness

Particularly effective in treating strains of malaria that are resistant to other medications

Upstream product

• 3299-61-4 N,N'-Di-p-tolyloxalamide 
• 10026-13-8 phosphorus pentachloride 
• 108-88-3 toluene 
• 98831-16-4 p-Toluidinium-oxalat 
• 79-37-8 oxalyl dichloride 
• 106-49-0 p-toluidine 
• 471-46-5 Oxalamide 

Downstream Products

• 608-05-9 5-methyl-indole-2,3-dione 
• 71740-28-8 4,4'-(di-p-tolyl-oxalodiimidoyl)-bis-morpholine 
• 167966-71-4 N,N'-Bis--1,2-bis-<4-tolylimino>-ethan-1,2-diamin 
• 167966-68-9 N,N'-Bis--1,2-bis-<4-tolylimino>-ethan-1,2-diamin 
• 167966-78-1 N,N'-Dicyclopentyl-1,2-bis-<4-tolylimino>-ethan-1,2-diamin 
• 167966-97-4 N,N'-Diphenyl-N,N'-dimethyl-1,2-bis-<4-tolylimino>-ethan-1,2-diamin 
• 167966-73-6 N,N'-Dibenzyl-1,2-bis-<4-tolylimino>-ethan-1,2-diamin 

Relevant articles and documents

Pyrrolo[3,2-b]pyrrole-based copolymers as donor materials for organic photovoltaics

A new accepter unit, pyrrolo[3,2-b]pyrrole-2,5-dione, was prepared and utilized for the synthesis of the conjugated polymers containing electron donor-acceptor pair for OPVs. Pyrrolo[3,2-b]pyrrole-2,5-dione unit, regioisomer of the known pyrrolo[3,4-c]pyrrole-1,4-dione, is originated from the structure of stable synthetic pigment. The new conjugated polymers with 1,4-diphenylpyrrolo[3,2-b]pyrrole-2,5-dione, thiophene and carbazole were synthesized using Suzuki polymerization to generate P1 and P2. The solid films of P1 and P2 show absorption bands with maximum peaks at about 377, 554 and 374, 542 nm and the absorption onsets at 670 and 674 nm, corresponding to band gaps of 1.85 and 1.84 eV, respectively. To improve the hole mobility of the polymer with 1,4-bis(4-butylphenyl)-pyrrolo[3,2-b]-pyrrole-2,5-dione unit, which was previously reported by us, the butyl group at the 4-positions of the N-substituted phenyl group was substituted with hydrogen and methyl group. The field-effect hole mobility of P2 is 9.6 × 10-5 cm2/Vs. The device with P2:PC71BM (1:2) showed VOC value of 0.84 V, JSC value of 5.10 mA/cm2, and FF of 0.33, giving PCE of 1.42%.

Fluorescent quencher molecules as well as methods and uses involving the same

The present invention relates to novel pyridinyl-isoquinoline-dione derivatives, methods of producing of these derivatives, conjugates comprising the novel pyridinyl-isoquinoline dione derivatives and (i) a solid support, or (ii) a biomolecule, methods of

A new route to ring-fused pyrazines: Imidazo[4,5-b]quinoxalines by a simple oxidation-annulation sequence

Novel tricyclic 4H-imidazo[4,5-b]quinoxalines were synthesized by a new orfto-annulation process starting from 4Himidazoles and cerammonium nitrate (CAN) as oxidation reagent in the presence of potassium carbonate as base. This reaction is interpreted as

A new synthesis of bis-enaminones via acylation of ketones

A short and efficient synthesis for a series of 1,6-diaryl-3,4- diarylaminohexa-2,4-diene-1,6-diones was developed. Based on the acylation-prototropism sequence during the reaction of various aryl methyl ketones with bis-imidoyl chlorides, the products were isolated in good yields. Substituted acetophenones, acetylthiophene, 3-acetylpyridine, and acetylferrocene can be integrated into this reaction as ketone component. Similarly, α-tetralone can be transformed with bis-electrophiles into the corresponding bis-enaminones. Treatment of 2-acetylpyridine with N,N′-bis(4-tolyl)ethanebis(imidoyl) dichloride yielded not only the expected bis-enaminone, but also a new quinolizine derivative which was structurally characterized by single crystal X-ray analysis. Analogously, pinacolone and cyclopropyl methyl ketone can readily be converted into bis-enaminones. Monoimidoyl chlorides showed the same reactivity, providing derivatives in high yields. Georg Thieme Verlag Stuttgart.

Tetrazoles: XL. Structure and basicity of 1,1′-disubstituted 5,5′-bitetrazoles

1,1′-Diaryl-5,5′-bitetrazoles, unlike 1,1′-dimethyl derivative, are Hammett bases which are much weaker than their monocyclic analogs. Bitetrazoles undergo monoprotonation in the H0 range from -5 to -9, and their pKBH+ values correla

On the Aminolysis of Bis-Imidoylchlorides of Oxalic Acid. Part I. Reaction with Aromatic and Aliphatic Amines

The reaction between bis-imidoylchlorides 2 derived from oxalic acid several aromatic and aliphatic amines was investigated.While primary aromatic amines need a thermical activation by refluxing, primary aliphatic amines give mainly at room temperature the amidines 3 in moderatly up to good yields.Proceeding from enantiomeric pure amines e.g. (R)- or (S)-1-phenylethylamine the new homochiral axalic amidines 3y and 3z with C2-symmetry were obtained.Several secondary amines react with the bis-imidoylchloride 2a to give via intramolecular cycloacylation derivatives of isatine.The new synthesized amidines 3 perform systems with a strong molecular dynamic like prototropic and E/Z-interconversion.All new compounds described were characterized by elemental analysis and spectroscopic methods.