33093-76-4

Basic information

• Product Name: 3,3-dibromo-1-phenylprop-2-en-1-one
• Synonyms: 3,3-dibromo-1-phenylprop-2-en-1-one
• CAS NO: 33093-76-4
• Molecular Weight: 289.954
• Mol File: 33093-76-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 3,3-dibromo-1-phenylprop-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3-dibromo-1-phenylprop-2-en-1-one(33093-76-4)
• EPA Substance Registry System: 3,3-dibromo-1-phenylprop-2-en-1-one(33093-76-4)

Safety Data

• Hazardous Substances Data: 33093-76-4(Hazardous Substances Data)

Upstream product

• 13735-81-4 1-styrenyloxytrimethylsilane 
• 558-13-4 carbon tetrabromide 
• 66324-10-5 tert-butyldimethyl(1-phenylvinyloxy)silane 
• 100-42-5 styrene 
• 536-74-3 phenylacetylene 
• 67-51-6 3,5-dimethyl-1H-pyrazole 
• 3876-61-7 1-benzoyl-2-bromoacetylene 
• 288-13-1 NH-pyrazole 
• 129993-18-6 1-vinyl-2-(1,1-biphenyl-4-yl)pyrrole 
• 56506-90-2 (dibromomethyl)(triphenyl)phosphonium bromide 
• 582-24-1 1-phenyl-2-hydroxyethanone 
• 1074-12-0 phenylglyoxal hydrate 
• 88917-08-2 3,3-Dibrom-acrylsaeure-bromid 
• 71-43-2 benzene 

Downstream Products

• 10250-60-9 1,5-dimethyl-3-phenyl-1H-pyrazole 
• 1226790-16-4 C₁₃H₁₄N₂ 
• 66870-43-7 1-methyl-5-(4-methylphenyl)-3-phenyl-1H-pyrazole 
• 53694-82-9 5-(4-chlorophenyl)-1-methyl-3-phenyl-1H-pyrazole 
• 66870-45-9 5-(4-methoxyphenyl)-1-methyl-3-phenyl-1H-pyrazole 
• 1188116-65-5 5-bromo-1-methyl-3-phenyl-1H-pyrazole 
• 19311-79-6 1-methyl-3,5-diphenyl-1H-pyrazole 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 

Relevant articles and documents

Synthesis of 2,2-di(pyrazol-1-yl)enones via the 2:1 coupling of pyrazoles and acylbromoacetylenes in solid alumina

Pyrazoles were reacted with acylbromoacetylenes in solid Al2O3 at room temperature to afford 2,2-di(pyrazol-1-yl)enones in 22–69% yield. The reaction proceeds via isolable intermediates, (Z)-2-bromo-2-(pyrazol-1-yl)enones. This unexpected 2:1 coupling is in contrast to similar reactions of pyrroles, furans and thiophenes, which give the corresponding acylethynyl derivatives. This reaction opens a one-pot route to inaccessible gem-dipyrazolylenones, which have potential applications as bidentate chelating ligands and building blocks for drug design.

Access to gem-Dibromoenones Enabled by Carbon-Centered Radical Addition to Terminal Alkynes in Water Solution

We herein report a novel and more practical approach to prepare gem-dibromoenones from terminal alkynes, tetrabromomethane (CBr4), and water in a single step. Mechanistic studies reveal that the generation of a tribromomethyl radical with the assistance of a persulfate salt (K2S2O8) is essential to this transformation. The reaction features readily available chemicals, a broad substrate scope, a green solvent, and mild reaction conditions, providing an efficient alternative for construction of halogen-substituted enones.

[Cu(dap)2Cl] as an efficient visible-light-driven photoredox catalyst in carbon-carbon bond-forming reactions

Copper sees the light of day: [Cu(dap)2Cl] proved to be an excellent photoredox catalyst for atom-transfer radical addition reactions, as well as for allylation reactions (see scheme), providing an attractive alternative to commonly used iridium- and ruthenium-based catalysts. Copyright