33295-47-5

Basic information

• Product Name: 2-Naphthalenecarboxylic acid, 4-Methoxy-, Methyl ester
• Synonyms: 2-Naphthalenecarboxylic acid, 4-Methoxy-, Methyl ester;Methyl 4-methoxy-2-naphthoate
• CAS NO: 33295-47-5
• Molecular Formula: C13H12O3
• Molecular Weight: 216.23258
• Mol File: 33295-47-5.mol
• Article Data: 3

Chemical Properties

• Melting Point: 202.0-202.5 °C
• Boiling Point: 349.5°C at 760 mmHg
• Flash Point: 145.3°C
• Appearance: /
• Density: 1.166g/cm³
• Vapor Pressure: 4.69E-05mmHg at 25°C
• Refractive Index: 1.589
• CAS DataBase Reference: 2-Naphthalenecarboxylic acid, 4-Methoxy-, Methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Naphthalenecarboxylic acid, 4-Methoxy-, Methyl ester(33295-47-5)
• EPA Substance Registry System: 2-Naphthalenecarboxylic acid, 4-Methoxy-, Methyl ester(33295-47-5)

Safety Data

• Hazardous Substances Data: 33295-47-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H12O3/c1-15-12-8-10(13(14)16-2)7-9-5-3-4-6-11(9)12/h3-8H,1-2H3

Upstream product

• 100-52-7 benzaldehyde 
• 34205-71-5 methyl 4-hydroxy-2-naphthalenecarboxylate 
• 74-88-4 methyl iodide 
• 1573-91-7 3-hydroxynaphthoic acid 
• 77-78-1 dimethyl sulfate 
• 59567-96-3 1,3-Dihydro-1,1-dimethoxyisobenzofuran 
• 292638-85-8 acrylic acid methyl ester 

Downstream Products

• 123239-64-5 4-methoxynaphthalene-2-carbaldehyde 

Relevant articles and documents

BENZOINDAZOLONE COMPOUND, AND INTERMEDIATE THEREOF

The present invention relates to a benzoindazolone compound, or a pharmaceutically acceptable salt, hydrate, solvate, enantiomer, diasteromer, tautomer or prodrug thereof; and an intermediate thereof. A compound according to the present invention is used as a substrate for NQO1 to facilitate a redox reaction of NQO1, and thus is expected to be developable as a medicine for preventing or treating inflammatory diseases.

1-Methoxyisobenzofuran: Formation from 1,3-Dihydro-1,1-dimethoxyisobenzofuran

1-Methoxyisobenzofuran is formed by treatment of 1,3-dihydro-1,1-dimethoxyisobenzofuran with either a trace of acetic acid in refluxing toluene or with LDA at 70 deg C.The requirements to obtain Diels-Alder adducts under both sets of conditions are examined, and various products are characterized.