33422-43-4Relevant articles and documents
One-pot reductive amination of carboxylic acids: a sustainable method for primary amine synthesis
Coeck, Robin,De Vos, Dirk E.
supporting information, p. 5105 - 5114 (2020/08/25)
The reductive amination of carboxylic acids is a very green, efficient and sustainable method for the production of (bio-based) amines. However, with current technology, this reaction requires two to three reaction steps. Here, we report the first (heterogeneous) catalytic system for the one-pot reductive amination of carboxylic acids to amines, with solely H2 and NH3 as the reactants. This reaction can be performed with relatively cheap ruthenium-tungsten bimetallic catalysts in the green and benign solvent cyclopentyl methyl ether (CPME). Selectivities of up to 99% for the primary amine could be achieved at high conversions. Additionally, the catalyst is recyclable and tolerant for common impurities such as water and cations (e.g. sodium carboxylate).
Aqueous solutions of geminal alkylammonium surfactants as a medium for reactions of long-chain amines
Mirgorodskaya,Kudryavtseva
experimental part, p. 42 - 48 (2009/05/30)
The formation of surfactant-hydrophobic amine mixed aggregates reduces the pK a of long-chain amines by 1-1.5 units compared with those in molecular solutions and is an important factor responsible for the high catalytic effect of the system in
Effect of micellar surfactant solutions on the reactivity of long-chain amines
Mirgorodskaya,Kudryavtseva,Zuev,Vylegzhanina
, p. 1849 - 1852 (2007/10/03)
The kinetics of the interaction of long-chain alkylamines with p-nitrophenyl laurate in aqueous micellar solutions of cetylpyridinium bromide was studied. It was found that the reactivity of the amines changes when mixed aggregates are formed and that it depends on the ratio between components of the system. A nonlinear increase in the molecular packing density of the mixed micelles with the amine concentration was recorded by spin probe EPR.