3354-55-0

Upstream product

• 88-18-6 2-tert-Butylphenol 
• 107-05-1 3-chloroprop-1-ene 
• 75-09-2 dichloromethane 
• 2089-03-4 1-allyloxy-2-tert-butylbenzene 
• 106-95-6 allyl bromide 

Downstream Products

• 57241-62-0 4-Allyl-2-tert-butyl-6-((Z)-propenyl)-phenol 
• 57241-61-9 4-Allyl-2-tert-butyl-6-((E)-propenyl)-phenol 
• 126268-22-2 2-n-propyl-4-(5'-hexynoyl)-6-t-butylphenol 
• 28338-27-4 Carbamic acid 2-allyl-6-tert-butyl-phenyl ester 

Relevant academic research and scientific papers

Water-Accelerated Claisen Rearrangements

Allyl aryl ethers undergo accelerated Claisen and [1,3] rearrangements in the presence of a mixture of trialkylalanes and water or aluminoxanes. The ratio of ortho-, meta-, and pora-Claisen products depends to a large extent on the presence of water and to a much lesser extent on the nature of the alane.

Method for treating multiple sclerosis

Provided is a method of treating multiple sclerosis employing certain aryl-substituted rhodanines.

Method of treating inflammatory bowel disease

Provided is a method of treating inflammatory bowel disease in mammals utilizing certain benzyl-substituted rhodanine derivatives. Also provided are novel benzyl-substituted rhodanine derivatives and pharmaceutical compositions thereof, as well as a novel process for selectively isolating in substantially pure enantiomeric form the enantiomers of certain racemic benzyl-substituted rhodanine derivatives.

Convenient synthesis of 2,4-cyclohexadien-1-ones by regioselective methylthiomethylation of phenols

A convenient synthesis of a variety of 2,4-cyclohexadien-1-ones 3-7 is deseribed. Reaction of various phenols 2 having appropriate substituents with an excess of S,S-dimethylsuccinimidosulfonium chloride (Corey-Kim reagent, 1) in the presence of triethyla

Method of treating type I diabetes

Provided is a method for treating Type I diabetes in mammals utilizing certain aryl-substituted rhodanine derivatives.

Process for the preparation of certain substituted aromatic compounds

The present invention involves process for the preparation of compounds having the chemical structure: STR1 wherein Ar--H is an aromatic compound which is activated to an electrophilic attack, and wherein --Y is an aliphatic group having a labile moiety,

Tert-butylphenyl compounds useful as anti-inflammatory agents

The present invention involves compounds having the structure: STR1 wherein: (a) --A1 is selected from the group consisting of --OH, --H, and --O2 CR; (b) --A2 is selected from the group consisting of unsubstituted or substituted, saturated or unsaturated, straight, branched and cyclic alkyl having from 1 to about 10 carbon atoms; (c)--A3 is selected from --C(CH3)3, --Si(CH3)3, and --CF3 ; and (d) --Y is selected from certain low molecular weight alkyl chains which terminate in specific unsaturated functional groups: STR2 and aldehydes in the form of their acetals; pharmaceutical compositions comprising such compounds; and methods for treating inflammation by administering such compounds.