33602-15-2Relevant academic research and scientific papers
A remarkably efficient Markovnikov hydrochlorination of olefins and transformation of nitriles into imidates by use of AcCl and an alcohol
Yadav, Veejendra K.,Babu, K. Ganesh
, p. 452 - 456 (2005)
HCl generated by mixing AcCl with EtOH brings about Markovnikov hydrochlorination of olefins in excellent yields. The products are isolated in states of high purity simply by removal of the volatile components under reduced pressure. Further, nitriles are transformed into imidate hydrochlorides on similar treatment with AcCl and an alcohol. This procedure for nitrile-imidate transformation is much more efficient than that used previously, which involved continuous passing of HCl gas into the solution of a nitrile in a solvent such as Et2O or benzene and an alcohol until one equivalent had been absorbed. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005.
PRENYLATION OF CAMPHENE - A CARBOCATIONIC ROUTE TO ISOSANTALENE AND ITS DERIVATIVES
Rahman, Azizur,Baeuml, Englbert,Klein, Herbert,Mayr, Herbert
, p. 4119 - 4124 (2007/10/02)
Camphene 1 is converted into 8-chloromethylcamphene 3 via Prins reaction.Treatment of 3 with zinc chloride/ether in the presence of isobutene gives the 1:1 adduct 11, from which isosantalene 7, its isomer 6, and the corresponding alcohol 5 are obtained.
