336105-43-2

Usage

Uses

Used in Organic Synthesis:
1-(4-BROMO-PHENYL)-2,2,2-TRIFLUORO-ETHYLAMINE HYDROBROMIDE is used as a reagent in organic synthesis for the production of pharmaceuticals, agrochemicals, and other fine chemicals. Its unique structure with a bromine atom and fluorine atoms allows for versatile reactions and the creation of a wide range of compounds.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 1-(4-BROMO-PHENYL)-2,2,2-TRIFLUORO-ETHYLAMINE HYDROBROMIDE is used as an intermediate in the synthesis of various drugs. Its presence in the molecular structure can contribute to the development of new medications with specific therapeutic properties.
Used in Agrochemical Development:
Similarly, in the agrochemical sector, 1-(4-BROMO-PHENYL)-2,2,2-TRIFLUORO-ETHYLAMINE HYDROBROMIDE is used as an intermediate for the synthesis of pesticides and other crop protection agents. Its role in these applications is to provide the necessary functional groups for the development of effective and targeted agrochemicals.
Used in Research and Development:
1-(4-BROMO-PHENYL)-2,2,2-TRIFLUORO-ETHYLAMINE HYDROBROMIDE is also utilized in the research and development of new compounds with potential biological activities. Its unique chemical properties make it a valuable tool for exploring novel chemical entities that could have applications in medicine, agriculture, and other fields.
Used in Laboratory Settings:
This chemical is primarily used in a laboratory setting and should be handled with caution, following proper safety protocols. Its reactivity and potential hazards necessitate careful management to ensure the safety of researchers and the integrity of experiments.

Upstream product

• 16184-89-7 4'-bromo-2,2,2-trifluoroacetophenone 
• 842169-80-6 1-(2,2,2-trifluoro)-1-(4-bromophenyl)ethylimine 
• 943731-44-0 C₁₆H₁₃BrF₃N 
• 336105-31-8 N-[(1S)-1-(4-bromophenyl)-2,2,2-trifluoro-ethyl]-(R)-2-methyl-propane-2-sulfinamide 
• 1448681-98-8 (N-Z)-N-[(4-bromophenyl)methylene]-(R)-2-methyl-propane-2-sulfinamide 
• 1122-91-4 4-bromo-benzaldehyde 
• 842169-79-3 N-[1-(4-bromophenyl)-2,2,2-trifluoroethylidene]-1,1,1-trimethylsilanamine 
• 842169-81-7 1-(4-bromo-phenyl)-2,2,2-trifluoro-1-methoxy-ethylamine 
• 1258542-31-2 (Rs,R)-N-(1-(4-bromophenyl)-2,2,2-trifluoroethyl)-tert-butanesulfinamide 

Downstream Products

• 778565-93-8 (1S)-1-(4-bromophenyl)-2,2,2-trifluoroethanamine 
• 1448682-01-6 N-[(1S)-1-(4-bromophenyl)-2,2,2-trifluoro-ethyl]methanesulfonamide 
• 1448682-02-7 N-[(1S)-2,2,2-trifluoro-1-(4-formylphenyl)ethyl]methanesulfonamide 
• 950482-84-5 N-[2,2,2-trifluoro-1-(4-hydroxyiminomethylphenyl)ethyl] isobutyramide 
• 950482-83-4 N-[2,2,2-trifluoro-1-(4-formylphenyl) ethyl] isobutyramide 

Relevant academic research and scientific papers

NOVEL BENZYL SULFONAMIDE COMPOUNDS USEFUL AS MOGAT-2 INHIBITORS

The present invention provides compounds of Formula I. Wherein Rl, L, and A are as described herein, or a pharmaceutical salt thereof, processes for preparing the compounds, and methods of treating a condition, such as hypertriglyceridemia, using the comp

One-pot asymmetric synthesis of α-trifluoromethylated amines from α-trifluoromethyl ketones

Diastereoselective reduction of (Rs)-N-tert-butanesulfinyl α-trifluoromethyl ketimines formed in situ from the corresponding α-trifluoromethyl ketones and N-tert-butanesulfinamide has been achieved, and either diastereomer of N-tert-butanesulfinyl α-trifl

Substituted bis-amide metalloprotease inhibitors

This invention relates to substituted bis-amide pyrimidine compounds of Formula (I), which are useful for the treatment of metalloprotease mediated diseases, in particular MMP-13 related diseases.

Synthesis of alpha fluoroalkyl amines

This invention describes the reaction of an alpha fluoroalkyl ketone with a bis(trialkylsilyl)amide to give a stable N-trialkylsilyl imine. Treatment of the N-trialkylsilyl imine with an alcohol leads to solvolysis of the trialkylsilyl group and yields a

REVERSIBLE INHIBITORS OF MONOAMINE OXIDASE A AND B

The instant invention relates to compounds of formula I, diagrammed below, wherein R3, E, D and Y are defined in the application, which are useful as reversible inhibitors of monoamine oxidase-B and/or monoamine oxidase-A, and therefore useful to treat or prevent neurological diseases or conditions in mammals, preferably humans.

Unprecedented catalytic asymmetric reduction of N-H imines

(Chemical Equation Presented) Addition of lithium bis(trimethylsilyl)amide to perfluorinated ketones 1a-j affords (E)-N-TMS-ketimines 2a-j that are reduced in situ to afford racemic perfluoromethylated amine hydrochloride salts 3a-j in 54-97% yields. Solv

Stereoselective nucleophilic trifluoromethylation of N-(tert-butylsulfinyl)imines by using trimethyl(trifluoromethyl)silane

A very general reaction is presented to achieve the nucleophilic transfer of "CF3" to chiral N-(tert-butylsulfinyl)imines in high yield and high stereoselectivity (see reaction scheme). Tetrabutylammonium difluorotriphenylsilicate (TBAT) functi