778565-93-8 Usage
General Description
"(S)-1-(4-Bromo-phenyl)-2,2,2-trifluoro-ethylamine" is a chemical compound that features an ethylamine core which is trifluorinated and has a 4-bromophenyl group attached to it. The (S)-denotation refers to the specific spatial arrangement of atoms in the molecule, meaning it is the 'left-hand' version in a chiral pair. Being trifluorinated indicates that it carries three fluorine atoms. Due to the strong electronegativity of fluorine, this may substantially influence the compound's reactivity and properties. The 4-bromophenyl group suggests potential uses in the manufacture of more complex pharmaceutical or agrochemical products, since brominated organic compounds are often involved in such synthesis. Specific information about this chemical's toxicity, synthesis, and usage would likely be contained within a safety data sheet or detailed publication.
Check Digit Verification of cas no
The CAS Registry Mumber 778565-93-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,7,8,5,6 and 5 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 778565-93:
(8*7)+(7*7)+(6*8)+(5*5)+(4*6)+(3*5)+(2*9)+(1*3)=238
238 % 10 = 8
So 778565-93-8 is a valid CAS Registry Number.
778565-93-8Relevant articles and documents
MALT1 MODULATORS AND USES THEREOF
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, (2022/04/22)
Provided herein are compounds, compositions, and methods useful for modulating MALT1 and tor treating related diseases, disorders, and conditions.
Silver-catalyzed formal [3+2]-cycloaddition of α-trifluoromethylated methyl isocyanides: a facile stereoselective synthesis of CF3-substituted heterocycles
Zhang, Xue,Wang, Xin,Gao, Yuelei,Xu, Xianxiu
, p. 2427 - 2430 (2017/03/01)
An Ag-catalyzed formal [3+2]-cycloaddition of α-trifluoromethylated methyl isocyanides with polar double bonds has been developed for the facile access to trifluoromethylated oxazolines, imidazolines and pyrrolines under mild conditions. The practicality of this chemistry is demonstrated by the gram-scale synthesis of oxazolines with excellent yields and facile transformations of the formed oxazolines to trifluoromethylated β-amino alcohols in quantitative yields.
N-(2-CYANO HETEROCYCLYL)PYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS
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Page/Page column 49-50, (2014/10/03)
Provided are compounds of Formula I, a JAK inhibitor, and use thereof for the treatment of JAK-mediated diseases by the application.