842169-80-6

Basic information

• Product Name: Benzenemethanimine, 4-bromo-a-(trifluoromethyl)-
• CAS NO: 842169-80-6
• Molecular Formula: C8H5BrF3N
• Molecular Weight: 252.034
• Mol File: 842169-80-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzenemethanimine, 4-bromo-a-(trifluoromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanimine, 4-bromo-a-(trifluoromethyl)-(842169-80-6)
• EPA Substance Registry System: Benzenemethanimine, 4-bromo-a-(trifluoromethyl)-(842169-80-6)

Safety Data

• Hazardous Substances Data: 842169-80-6(Hazardous Substances Data)

Upstream product

• 842169-79-3 N-[1-(4-bromophenyl)-2,2,2-trifluoroethylidene]-1,1,1-trimethylsilanamine 
• 16184-89-7 4'-bromo-2,2,2-trifluoroacetophenone 
• 67-56-1 methanol 

Downstream Products

• 778565-93-8 (R)-1-(4-bromophenyl)-2,2,2-trifluoroethanamine 
• 336105-43-2 (1S)-1-(4-bromophenyl)-2,2,2-trifluoroethanamine hydrochloride 

Relevant articles and documents

Tertiary amine compound, bisphosphine ligand, and intermediate and preparation method of tertiary amine compound

The invention discloses a tertiary amine compound, a bisphosphine ligand, and an intermediate and a preparation method of the tertiary amine compound, and provides a tertiary amine compound preparation method, which comprises: under the protection of a ga

Enantioselective Friedel–Crafts Alkylation Reaction of Heteroarenes with N-Unprotected Trifluoromethyl Ketimines by Means of Chiral Phosphoric Acid

An enantioselective Friedel–Crafts alkylation reaction of pyrroles and indoles with N-unprotected trifluoromethyl ketimines by use of chiral phosphoric acid provided α-trifluoromethylated primary amines bearing chiral tetrasubstituted carbon centers in high yields and with high to excellent enantioselectivities. The present reaction is unique to N-unprotected trifluoromethyl ketimines. No reaction took place with N-p-methoxyphenyl (PMP)-substituted ketimine. Corresponding α-trifluoromethylated amines were transformed without loss of enantioselectivity.

Unprecedented catalytic asymmetric reduction of N-H imines

(Chemical Equation Presented) Addition of lithium bis(trimethylsilyl)amide to perfluorinated ketones 1a-j affords (E)-N-TMS-ketimines 2a-j that are reduced in situ to afford racemic perfluoromethylated amine hydrochloride salts 3a-j in 54-97% yields. Solv