3364-78-1

Basic information

• Product Name: 2-CHLOROMETHYL-THIAZOLE
• Synonyms: 2-CHLOROMETHYL-THIAZOLE;CHEMBRDG-BB 4016914;THIAZOLE, 2-(CHLOROMETHYL)-;2-Chloromethythiazole;2-(Chloromethyl)-1,3-thiazole
• CAS NO: 3364-78-1
• Molecular Formula: C₄H₄ClNS
• Molecular Weight: 133.6
• Product Categories: Thiazoles
• Mol File: 3364-78-1.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 182℃
• Flash Point: 64℃
• Appearance: /
• Density: 1.338
• Vapor Pressure: 1.15mmHg at 25°C
• Refractive Index: 1.564
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• PKA: 2.00±0.10(Predicted)
• CAS DataBase Reference: 2-CHLOROMETHYL-THIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLOROMETHYL-THIAZOLE(3364-78-1)
• EPA Substance Registry System: 2-CHLOROMETHYL-THIAZOLE(3364-78-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 3364-78-1(Hazardous Substances Data)

Usage

Uses

2-(Chloromethyl)thiazole was used for bisphosphonates preparation and structure-related bone antiresorptive properties. It was also used for preparation and substitution reaction of triphenylphosphine.

InChI:InChI=1/C4H4ClNS/c5-3-4-6-1-2-7-4/h1-2H,3H2

Upstream product

• 14542-12-2 (1,3-thiazol-2-yl)methanol 
• 10200-59-6 Thiazole-2-carbaldehyde 

Downstream Products

• 115754-94-4 thiazol-2-ylmethyltriphenylphosphonium chloride 
• 154212-60-9 N-methyl-N-<(2-isopropyl-4-thiazolyl)methyl>amine 
• 936340-62-4 3-(3-(4-(thiazol-2-ylmethoxy)benzyl)isoxazol-5-yl)pyridin-2-amine 
• 101010-74-6 2-cyanomethyl-thiazole 
• 851545-78-3 2-((2-chloro-4-nitrophenoxy)methyl)thiazole 

Relevant articles and documents

INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF

The invention provides a class of compounds as inhibitors of influenza virus replication, preparation methods thereof, pharmaceutical compositions containing these compounds, and uses of these compounds and pharmaceutical compositions thereof in the treatment of influenza.

Hetero-aromatic compound and its use in medicine (by machine translation)

The invention discloses heteroaromatic compound and its use in medicine, in particular, the invention provides a hetero-aromatic compound or its stereoisomers, geometric isomers, tautomers, racemate, nitrogen oxide, hydrate, solvate, metabolite, pharmaceutically acceptable salt or prodrug, and containing said pharmaceutical composition; the invention also discloses the compound or its pharmaceutical compositions in use for preparing a medicament, and in the treatment of autoimmune diseases or proliferative diseases of application. (by machine translation)

HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK

Disclosed herein are new heterocyclic compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibiting PAS Kinase (PASK) activity in a human or animal subject are also provided for the treatment of diseases such as diabetes mellitus.