33707-55-0

Upstream product

• 551959-28-5 3,4-bis[(4-methoxyphenyl)thio]-3-cyclobutene-1,2-dione 
• 70744-47-7 (p-methoxyphenyl)tri-n-butylstannane 
• 5720-07-0 4-methoxyphenylboronic acid 
• 2132-62-9 4,4'-dimethoxydiphenylacetylene 
• 67-64-1 acetone 
• 69009-33-2 3-chloro-4-(4-methoxyphenyl)-3-cyclobutene-1,2-dione 
• 100-66-3 methoxybenzene 
• 768-60-5 4-methoxyphenylacetylen 
• 33703-60-5 1-(4-Chloro-3,3,4-trifluoro-cyclobut-1-enyl)-4-methoxy-benzene 
• 33703-62-7 3-(4-methoxyphenyl)-3-cyclobutene-1,2-dione 
• 2892-63-9 3,4-Dichlorocyclobut-3-ene-1,2-dione 
• 33703-72-9 2-Hydroxy-3,4-bis-(4-methoxy-phenyl)-cyclobut-2-enone 

Relevant academic research and scientific papers

Silver catalyzed decarbonylative [3 + 2] cycloaddition of cyclobutenediones and formamides

As an important moiety in natural products, N,O-acetal has attracted wide attention in the past few years. An efficient method to construct N,O-acetal has been developed. Using silver catalyst, cyclobutenediones were smoothly converted to the corresponding γ-aminobutenolides in the presence of formamides, in which cyclobutenediones likely proceed with a key decarbonylative [3 + 2] cycloaddition process. In this way, a series of products with varied substituents were isolated in moderate yield and fully characterized.

Synthesis and antitumor activity of novel 3,4-diaryl squaric acid analogs

A series of novel 3,4-diaryl squaric acid analogs 4a-r related to combretastatin A-4 (CA4) using squaric acid as the cis-restricted linker were prepared and studied for their anticancer activity against selected human cancer cell lines. New compounds 4g,

Pd-catalyzed, Cu(I)-mediated cross-couplings of bisarylthiocyclobutenediones with boronic acids and organostannanes

(Chemical Equation Presented) Bisarylthiocyclobutenedione 7 reacted smoothly with a variety of both organostannanes and (hetero)arylboronic acids in the presence of a catalytic amount of Pd and a stoichiometric amount of CuTC to produce symmetrical disubstituted cyclobutenediones in yields that range from 37 to 94% (18 examples).

Reactions of carbonyl compounds in basic solutions. Part 25. 1 the mechanism of the base-catalysed ring fission of 3,4-diphenylcyclobut-3-ene-1,2-diones

The rate coefficients for the base-catalysed ring fission of a series of substituted 3,4-diphenylcyclobut-3-ene-1,2-diones to give the corresponding (Z)-2-oxo-3,4-diphenylbut-3-enoic acids have been determined in 50% (v/v) aqueous dimethyl sulfoxide (DMSO