33815-54-2

Upstream product

• 7474-65-9 (E)-2-phenylchalcone 
• 100-52-7 benzaldehyde 
• 501-65-5 diphenyl acetylene 
• 6630-33-7 ortho-bromobenzaldehyde 
• 53347-50-5 2,3-diphenyl-1H-inden-1-ol 
• 108-86-1 bromobenzene 
• 16618-72-7 3-phenyl-1-indanone 
• 4023-77-2 1-benzoyl-1,2-diphenylethylene 
• 1801-42-9 2,3-diphenyl-1H-inden-1-one 
• 94880-38-3 2,3,3-triphenyl-propionyl chloride 
• 144017-77-6 (E)-1-(2-chlorophenyl)-3-phenylprop-2-en-1-one 

Downstream Products

• 38274-35-0 1,2,3-triphenylindene 
• 51944-58-2 2,3-diphenyl-1-p-tolyl-inden-1-ol 
• 1801-42-9 2,3-diphenyl-1H-inden-1-one 
• 33815-51-9 2r,3t-Diphenyl-1-benzyl-indan-1ξ-ol 
• 7495-10-5 (+/-)-trans-2,3-diphenyl-indan-1-one-(2,4-dinitro-phenylhydrazone) 
• 70550-46-8 trans, cis-1,2,3-triphenylindane 

Relevant academic research and scientific papers

Synthesis of diastereoisomeric 1,2,3-triphenylindans

The stereoisomers of 1,2,3-triphenylindans were synthesized via 1,2,3-triphenylindan-1-ols. The configurational assignments of all the compounds were made by chemical and spectroscopic methods. An unexpected compound was isolated as a by-product of the Gr

Synthesis of Indanones and Spiroindanones by Diastereoselective Annulation Based on a Hydrogen Autotransfer Strategy

An unprecedented nickel-catalyzed domino reductive cyclization of alkynes and o-bromoaryl aldehydes is described. The reaction features broad substrate scope and is tolerant of a variety of functional groups, providing straightforward access to biologically significant indanones and spiroindanone pyrrolidine derivatives in good yields with excellent regio- and diastereoselectivity. Preliminary mechanistic studies have shown that indanones are formed by the cyclization of o-bromoaryl aldehydes and alkynes to form indenol intermediates, followed by hydrogen autotransfer.

Construction of Halofunctionalized Indenes via a Cascade Prins-Nazarov Cyclization Promoted by Dual Roles of BX3

Halofunctionalization of various unactivated arylalkynes to the corresponding 1H-indenes in the presence of a particular class of carboxaldehydes and boron trihalides (BX3, X=F, Cl, Br, I) is described. A diverse array of halofunctionalized indenes substituted with a heterocycle has been synthesized regioselectively with BX3 as a promotor for the carbocyclization and a source of X? for halogenation. This reaction proceeds via a formal halogenative [4+1] cycloaddition between arylalkynes and carboxaldehydes promoted by boron trihalides to generate halofunctionalized indenes. The usefulness of the halofunctionalized indenes was demonstrated by their conversion to other derivatives via coupling, nucleophilic substitution, and oxidation. (Figure presented.).

Palladium-catalyzed asymmetric reductive Heck reaction of aryl halides

Asymmetric reductive Heck reaction of aryl halides is realized in high stereoselectivity. Hydrogen-bond donors, trialkylammonium salts in a glycol solvent, were used to promote halide dissociation from neutral arylpalladium complexes to access cationic, stereoselective pathways.

Stereoselective palladium-catalyzed α-arylation of 3-aryl-1-indanones: An asymmetric synthesis of (+)-pauciflorol F

Highly stereoselective, palladium-catalyzed α-arylation reactions of 3-aryl-1-indanones with aryl bromides are described. The use of sodium tert-butoxide as a base in this process is required to elevate the efficiencies and stereoselectivities of these re

Toward the synthesis of caraphenol C: Substituent effect on the Nazarov cyclization of 2-arylchalcones

A mild and versatile synthesis of cis-2,3-diarylindanones using a Nazarov cyclization strategy was reported. The substituent effect on the stereochemistry of the cyclization was discussed. Georg Thieme Verlag Stuttgart.

Novel one-pot approach to synthesis of indanones Through Sb(V)-catalyzed reaction of phenylalkynes with aldehydes

Catalytic SbF5 and the use of EtOH as an additive efficiently converted a mixture of phenylalkynes and aldehydes to indanone compounds in one pot, and the reaction stereoselectively afforded the corresponding 2,3-disubstituted indanones as a single trans-isomer.

The Friedel-Crafts arylation of α-substituted chalcones revisited: Highly stereospecific synthesis of trans-2,3-diphenyl-indan-1-one derivatives

The Lewis or protic acid promoted cycloisomerization of 1,2,3-triphenylpropenone in nitroethane as solvent has given trans-2,3-diphenyl-indan-1-one with complete diastereoselection in good to excellent chemical yield.

Reaktionen mit Radikalanionen, IV. Synthese von Mono- und Diketonen aus Carboxyl- und α,β-ungesaettigten Carbonyl-Verbindungen

1,2-Diketones of the benzil type were obtained in the reaction of aromatic carboxylic compounds with lithium naphthalenide.The scope of this reaction was investigated. α,β-Unsaturated ketones yielded hydrodimerisation, hydrogenation and hydroxylation products.