4023-77-2

Basic information

• Product Name: 1,2,3-triphenylprop-2-en-1-one
• CAS NO: 4023-77-2
• Molecular Formula: C₂₁H₁₆O
• Molecular Weight: 284.3511
• Mol File: 4023-77-2.mol
• Article Data: 31

Chemical Properties

• Boiling Point: 432.7°C at 760 mmHg
• Flash Point: 188.9°C
• Density: 1.128g/cm³
• Vapor Pressure: 1.09E-07mmHg at 25°C
• Refractive Index: 1.65
• CAS DataBase Reference: 1,2,3-triphenylprop-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3-triphenylprop-2-en-1-one(4023-77-2)
• EPA Substance Registry System: 1,2,3-triphenylprop-2-en-1-one(4023-77-2)

Safety Data

• Hazardous Substances Data: 4023-77-2(Hazardous Substances Data)

Usage

General Description

1,2,3-triphenylprop-2-en-1-one is a chemical compound with a molecular formula C21H16O. It is a yellow crystalline solid that is commonly used as a building block in organic synthesis. 1,2,3-triphenylprop-2-en-1-one is a member of the aromatic ketone family and contains a phenyl group attached to the carbon-carbon double bond. It is often employed in the production of pharmaceuticals, agrochemicals, and fine chemicals. Additionally, 1,2,3-triphenylprop-2-en-1-one is known for its role as a reagent in various chemical reactions, including the synthesis of complex organic molecules. Due to its versatile nature and reactivity, this compound is of interest to researchers and industry professionals in the field of organic chemistry.

Upstream product

• 7664-93-9 sulfuric acid 
• 74897-80-6 (3-oxo-1,2,3-triphenyl-propyl)-malonic acid diethyl ester 
• 5909-74-0 (4-chlorobenzylidene)phenylamine N-oxide 
• 16510-49-9 1,2,3-triphenylcyclopropene 
• 60-29-7 diethyl ether 
• 100-52-7 benzaldehyde 
• 6921-34-2 benzylmagnesium chloride 
• 451-40-1 phenyl benzyl ketone 
• 7647-01-0 hydrogenchloride 
• 806-71-3 1,2,3,4-tetraphenyl-1,3-butadiene 
• 64-19-7 acetic acid 
• 100-47-0 benzonitrile 
• 39672-25-8 3-azido-1,2,3-triphenylcyclopropene 
• 50-00-0 formaldehyd 

Downstream Products

• 105782-49-8 3-bromo-1,2,3-triphenyl-propan-1-one 
• 493012-18-3 3,4-diphenyl-4-(1-phenyl-propyl)-[1,2]dioxetan-3-ol 
• 7476-12-2 phenyl 1,3,3-triphenylprop-2-enyl ketone 
• 876488-69-6 1,2,3,3-tetraphenyl-prop-1-en-1-ol 
• 500778-04-1 2-bromo-1,2,3,3-tetraphenyl-propan-1-one 
• 7469-01-4 3-chloro-1,2,3-triphenyl-propan-1-one 
• 7512-68-7 1,2,3-triphenyl-propenone oxime 
• 89624-49-7 2,3-diphenylinden-1-yl acetate 
• 4842-45-9 1,2,3-triphenylpropan-1-one 
• 102477-85-0 α,β-Diphenyl-β-mercapto-propiophenon 
• 65-85-0 benzoic acid 
• 22711-24-6 4-nitrobenzil 
• 62-23-7 4-nitro-benzoic acid 
• 7474-64-8 cis-2,3-diphenyl-2,3-dihydro-1H-inden-1-one 

Relevant articles and documents

Flexible Construction of Functionalized-Pyrroles under Palladium or Copper Catalysis in the Presence of BF3 ? Et2O

We have developed a flexible approach enabling the access to highly functionalized pyrroles under palladium or copper catalysis in the presence of BF3 ? Et2O. This catalytic methodology utilizes commercially available amines as react

Method for synthesizing alpha, beta unsaturated ketone

The invention belongs to the technical field of chemical synthesis, and particularly relates to a method for synthesizing alpha, beta unsaturated ketone. The reaction adopts a synergetic catalysis system of Co(acac)2 or Co(acac)3, a ligand and AlMe3, provides a way for economically and selectively synthesizing alpha, beta unsaturated ketones by atoms, and has the advantages of high yield and wide substrate range.

Synergistic Activation of Amides and Hydrocarbons for Direct C(sp3)–H Acylation Enabled by Metallaphotoredox Catalysis

The utilizations of omnipresent, thermodynamically stable amides and aliphatic C(sp3)?H bonds for various functionalizations are ongoing challenges in catalysis. In particular, the direct coupling between the two functional groups has not been realized. Here, we report the synergistic activation of the two challenging bonds, the amide C?N and unactivated aliphatic C(sp3)?H, via metallaphotoredox catalysis to directly acylate aliphatic C?H bonds utilizing amides as stable and readily accessible acyl surrogates. N-acylsuccinimides served as efficient acyl reagents for the streamlined synthesis of synthetically useful ketones from simple C(sp3)?H substrates. Detailed mechanistic investigations using both computational and experimental mechanistic studies were performed to construct a detailed and complete catalytic cycle. The origin of the superior reactivity of the N-acylsuccinimides over other more reactive acyl sources such as acyl chlorides was found to be an uncommon reaction pathway which commences with C?H activation prior to oxidative addition of the acyl substrate.