33953-86-5

Usage

Uses

Used in Pharmaceutical and Agrochemical Synthesis:
2,2,2-Trifluoroacetaldehyde hydrate is used as a key intermediate for the synthesis of various pharmaceuticals and agrochemicals. Its presence in these compounds contributes to their efficacy and performance in their respective applications.
Used in Organic Reactions as a Solvent:
In the realm of organic chemistry, 2,2,2-Trifluoroacetaldehyde hydrate is utilized as a solvent, facilitating a wide range of reactions and processes. Its unique properties make it suitable for dissolving a variety of substances and promoting specific chemical transformations.
Used in the Production of Fluorine-Containing Polymers:
2,2,2-Trifluoroacetaldehyde hydrate plays a crucial role in the production of fluorine-containing polymers. These polymers are known for their exceptional properties, such as chemical resistance, thermal stability, and non-stick characteristics, making them ideal for various industrial applications.
Used in the Manufacturing of Other Fluorinated Compounds:
As an intermediate, 2,2,2-Trifluoroacetaldehyde hydrate is essential in the manufacturing process of other fluorinated compounds. These compounds are widely used in various industries, including electronics, materials science, and chemical manufacturing, due to their unique properties.
Used in Research and Development Applications:
2,2,2-Trifluoroacetaldehyde hydrate is also employed in research and development settings, where its unique properties and reactivity are explored for potential new applications and advancements in various fields.
It is important to handle 2,2,2-Trifluoroacetaldehyde hydrate with care, as it may cause irritation to the skin, eyes, and respiratory tract, and prolonged exposure can be harmful. Proper safety measures should be taken to minimize any potential risks associated with its use.

Upstream product

• 75-46-7 trifluoromethan 
• 383-63-1 ethyl trifluoroacetate, 
• 420-46-2 2,2,2-trifluoroethanol 
• 75-89-8 2,2,2-trifluoroethanol 

Downstream Products

• 86884-21-1 rac-4,4,4-trifluoro-3-hydroxybutanoic acid 

Relevant academic research and scientific papers

Process for preparing trifluoroacetaldehyde hydrate from 1,1,1-halothane

The invention discloses a process for preparing trifluoroacetaldehyde hydrate from 1,1,1-halothane. The process comprises the following steps of preheating a raw material mixture consisting of 1,1,1-halothane, oxygen gas and nitrogen gas; then, injecting the mixture into a fixed bed reactor; using Fe2O3/AlF3 or CuO/AlF3 as a catalyst; performing reaction at 0.1 to 3 mPa at 100 to 500 DEG C, wherein the reaction is continuously performed; adsorbing products at an outlet; and separating out the trifluoroacetaldehyde hydrate. The process for preparing the trifluoroacetaldehyde hydrate provided by the invention has the advantages that the conversion rate of the 1,1,1-halothane can reach 16 to 39 percent; the selectivity of the trifluoroacetaldehyde hydrate can reach 20 percent or higher; through the process, the 1,1,1-halothane can be directly converted into the trifluoroacetaldehyde hydrate; the reaction process is simple; the product can be easily separated; the purity of the obtained trifluoroacetaldehyde hydrate can reach 95 percent or higher. The trifluoroacetaldehyde hydrate capable of being applied to important chemical products can be prepared and produced at high efficiency and low cost.

CATALYST FOR OXIDIZING 2,2,2-TRIFLUOROETHANOL AND METHOD FOR PRODUCING TRIFLUOROACETALDEHYDE

A catalyst for oxidizing 2,2,2-trifluoroethanol to form trifluoroacetaldehyde. The catalyst has a long life and achieves high conversion and selectivity. The catalyst of the present invention comprises one or more metal oxides, including at least vanadium oxide, and zirconia as a carrier.

Perfluoroalkylation method and reagent therefor

PCT No. PCT/FR96/01854 Sec. 371 Date Feb. 22, 1999 Sec. 102(e) Date Feb. 22, 1999 PCT Filed Nov. 22, 1996 PCT Pub. No. WO97/19038 PCT Pub. Date May 29, 1997The subject-matter of the present invention is a process of use in perfluoroalkylation and a reactant for making use of this process. This process is defined in that it comprises a stage in which a material of formula RfH and a base (or a species capable of generating a base) are brought into contact, in a polar and anhydrous medium, with a substrate carrying at least one electrophilic functional group. Application to organic synthesis.

Chemical process for manufacturing trifluoroacetaldehyde hydrate or trifluoroacetalde hemiacetal

A process for the manufacture of trifluoroacetaldehyde, or a hydrate or hemiacetal thereof, which comprises reduction of an ester of trifluoroacetic acid with a borohydride reducing agent in a hydroxylic solvent to form trifluoroacetaldehyde hydrate or hemiacetal; whereafter if the free aldehyde is required, water or alcohol is removed from the hydrate or hemiacetal respectively using conventional procedures.