33963-55-2

Usage

Chemical Properties

white to light yellow or light green powder and/or

InChI:InChI=1/C8H8O4S/c1-13(11,12)7-5-3-2-4-6(7)8(9)10/h2-5H,1H3,(H,9,10)/p-1

Upstream product

• 69159-80-4 3-methoxy-benzo[b]thiophene-1,1-dioxide 
• 14092-00-3 methyl o-tolyl sulfide 
• 1127-35-1 1-benzothiophen-3(2H)-one 1,1-dioxide 
• 623-11-0 1-methyl-4-nitrosobenzene 
• 61670-15-3 3-hydroxy-1-benzothiophene-1,1-dioxide 
• 3724-10-5 2-(methylthio)benzoic acid 
• 19093-34-6 2-(methylsulfinyl)benzoic acid 
• 49639-13-6 2-methylsulfonylbenzoyl chloride 
• 412345-55-2 3-hydroxy-1,1-dioxo-1λ⁶-benzo[b]thiophene-2-carboxylic acid ethyl ester 

Downstream Products

• 89942-56-3 2-(methylsulfonyl)benzonitrile 
• 220848-31-7 4-[[(2,6-Dichlorophenyl)carbonyl]amino]-N-[(2-methylsulfonylphenyl)carbonyl]-L-phenylalanine methyl ester 
• 583881-11-2 C₂₂H₂₆Cl₂N₂O₅S 
• 13736-79-3 1-methanesulfonyl-2-methoxy-benzene 
• 1381800-45-8 potassium 2-(methylsulfonyl)benzoate 
• 1360148-83-9 methyl phenyl-2-d sulfone 
• 1221268-92-3 N-(5-methyl-1H-pyrazol-3-yl)-2-(4-(2-(methylsulfonyl)benzoyl)-1-piperazinyl)-pyrrolo[2,1-f][1,2,4]triazine-4-amine 
• 1094024-91-5 N',N'-dimethyl-2-methanesulfonylbenzohydrazide 

Relevant academic research and scientific papers

Substituent effects on the base-catalysed hydrolysis of phenyl esters of ortho-substituted benzoic acids

Fourteen model phenyl esters of 2-substituted benzoic acids were synthesised. Structures and purity of model compounds were confirmed by 1H and 13C NMR spectroscopy, as well as by HPLC and elemental analysis. Kinetics of base-catalysed hydrolysis of model phenyl esters occurring by the BAC2 mechanism were measured by UV spectrophotometry in 50% (v/v) aqueous dimethyl sulfoxide solutions at 25 °C under pseudo-first-order reaction conditions (c(NaOH) = 0.001-1.0 mol 1-1). Linear relation between JE- and log kobs with the slope close to unity was found for all model compounds. Neither one-parameter nor multiparameter Hammett-type description of variability of experimental data obtained for phenyl esters of 2-substituted benzoic acids was found. Two groups (conjugating and non-conjugating) were created by division of ortho-substituents in ortho-position using the AISE theory, based on their interaction with the reaction centre.

Separation of Polar and Steric Effects: Reactions of ortho-Substituted Benzoate and 3-Substituted 2-Naphthoate Ions with Picryl Bromide

Rate constants for the reactions of ortho-substituted benzoate and 3-substituted 2-naphthoate ions with picryl bromide have been determined at 30 deg C, 40 deg C and 50 +/- 0.1 deg C in 80percent methanol-20percent water (v/v) mixtures.Electron-donating groups increase the rate, while electron-withdrawing groups decrease the rate.The rate data are analysed through multiple correlations involving electronic and steric terms associated with substituents.The steric term is rate-accelerating.