3400-22-4

Basic information

• Product Name: 4-METHOXY-N-METHYLBENZAMIDE
• Synonyms: 4-METHOXY-N-METHYLBENZAMIDE;BenzaMide, 4-Methoxy-N-Methyl-
• CAS NO: 3400-22-4
• Molecular Formula: C₉H₁₁NO₂
• Molecular Weight: 165.19
• Mol File: 3400-22-4.mol
• Article Data: 72

Chemical Properties

• Boiling Point: 322.7 °C at 760 mmHg
• Flash Point: 149 °C
• Appearance: /
• Density: 1.074 g/cm³
• Vapor Pressure: 0.000274mmHg at 25°C
• Refractive Index: 1.517
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4-METHOXY-N-METHYLBENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHOXY-N-METHYLBENZAMIDE(3400-22-4)
• EPA Substance Registry System: 4-METHOXY-N-METHYLBENZAMIDE(3400-22-4)

Safety Data

• Hazardous Substances Data: 3400-22-4(Hazardous Substances Data)

Usage

General Description

4-Methoxy-N-methylbenzamide is a chemical compound with the molecular formula C9H11NO2. It is a derivative of benzamide with a methoxy and a methyl group attached to the nitrogen and carbon atoms, respectively. The compound is used in organic synthesis and pharmaceutical research, and has potential applications in the development of new drugs and therapeutic agents. Its structural properties and reactivity make it an important building block in the synthesis of various organic compounds, and it is also used as a reagent in the preparation of other chemical substances. Additionally, 4-methoxy-N-methylbenzamide is of interest to researchers studying the structure-activity relationships of biologically active compounds.

InChI:InChI=1/C9H11NO2/c1-10-9(11)7-3-5-8(12-2)6-4-7/h3-6H,1-2H3,(H,10,11)

Upstream product

• 100-07-2 4-methoxy-benzoyl chloride 
• 74-89-5 methylamine 
• 85462-16-4 N-Methyl-O-p-nitrophenylsulphonylhydroxylamine 
• 123-11-5 4-methoxy-benzaldehyde 
• 203731-09-3 4-methoxybenzylidenemethylamine N-oxide 
• 134814-88-3 Benzoic acid [(4-methoxy-benzoyl)-methyl-amino]-methyl ester 
• 81238-43-9 4,4'-dimethoxy-N-methylbenzanilide 
• 100-09-4 4-methoxybenzoic acid 
• 3400-21-3 2-methyl-3-anisyloxaziridine 
• 30364-57-9 4-methoxybenzoic acid 2,5-dioxo-1-pyrrolidinyl ester 
• 696-63-9 4-Methoxybenzenethiol 
• 201230-82-2 carbon monoxide 
• 622-29-7 N-Benzylidenemethylamine 
• 13214-64-7 N-(4-methoxybenzoyl)glycine 

Downstream Products

• 671220-10-3 acetyl-(4-methoxy-benzoyl)-methyl-amine 
• 702-24-9 4-methoxy-N-methylbenzylamine 
• 68823-03-0 5-(4-chloro-phenyl)-2-(4-methoxy-phenyl)-3-methyl-4,6-dioxo-5,6-dihydro-4H-[1,3]oxazinium betaine 
• 68823-09-6 2-(4-methoxy-phenyl)-3,5-dimethyl-4,6-dioxo-5,6-dihydro-4H-[1,3]oxazinium betaine 
• 68823-10-9 5-ethyl-2-(4-methoxy-phenyl)-3-methyl-4,6-dioxo-5,6-dihydro-4H-[1,3]oxazinium betaine 
• 68823-15-4 2-(4-methoxy-phenyl)-3-methyl-4,6-dioxo-5-phenyl-5,6-dihydro-4H-[1,3]oxazinium betaine 
• 68823-12-1 5-benzyl-2-(4-methoxy-phenyl)-4,6-dioxo-3-methyl-5,6-dihydro-4H-[1,3]oxazinium betaine 
• 68823-02-9 2,5-bis-(4-methoxy-phenyl)-3-methyl-4,6-dioxo-5,6-dihydro-4H-[1,3]oxazinium betaine 
• 134814-88-3 Benzoic acid [(4-methoxy-benzoyl)-methyl-amino]-methyl ester 
• 132606-41-8 4-Methoxy-N-{(4-methoxy-phenyl)-[(Z)-methylimino]-methyl}-N-methyl-benzamide 
• 78554-86-6 N-methyl-p-anisylimidoyl chloride 
• 100-09-4 4-methoxybenzoic acid 
• 212501-06-9 5-methoxy-3-(3,4,5-trimethoxyphenyl)phthalide 
• 128174-48-1 5-Methoxy-3-((E)-styryl)-3H-isobenzofuran-1-one 

Relevant articles and documents

HYDRATION OF N-MONOSUBSTITUTED AMIDES IN THE BINARY SOLVENTS DIOXANE-D2O AND DIOXANE-H2O

The molecular-level stucture of hydrated N-monosubstituted amides in aqueous media has been studied by measuring the infrared absorption spectra due to the C=O stretching (or amide I band) of a series of N-monosubstituted amides (RCONHR') in dioxan-D2O and dioxan-H2O mixtures.Three kinds of hydrated species of the secondary amides have been identified, namely monohydrated amide (II) (at the amide oxygen), dihydrated amide (III) (monohydrated at both the amide oxygen and the amide NH), and trihydrated amide (IV) (dihydrated at the amide oxygen and monohydrated at the amide NH).With increasing water content, the relative amounts of the hydrated amides increases in the order IIIIIIV.In pure heavy water, all of the amide molecules are hydrated, and two or three hydration states are in equilibrium.The degree of hydration is little influenced by the electronic character of the substituent R, whereas it is considerably influenced by the hydrophobic character of the substituent R'.As to the H/D isotope effect, the hydrogen bonding strength of C=O...HOH is stronger than that of C=O...DOD for N-alkylbenzamides.

Unexpected Z/E isomerism of N-methyl-O-phosphothioyl benzohydroxamic acids, their oxyphilic reactivity and inertness to amines

Thiophosphinoylation of N-methyl p-substituted benzohydroxamic acids using disulfanes (method A) or diphenylphosphinothioyl chloride (method B) provides only one conformer of the respective O-phosphothioyl derivative (X-ray and NMR analysis). Undergoing t

Assemblies of 1,4-Bis(diarylamino)naphthalenes and Aromatic Amphiphiles: Highly Reducing Photoredox Catalysis in Water

Host-guest assemblies of a designed 1,4-bis(diarylamino)naphthalene and V-shaped aromatic amphiphiles consisting of two pentamethylbenzene moieties bridged by an m -phenylene unit bearing two hydrophilic side chains emerged as highly reducing photoredox catalysis systems in water. An efficient demethoxylative hydrogen transfer of Weinreb amides has been developed. The present supramolecular strategy permits facile tuning of visible-light photoredox catalysis in water.