341-41-3

Usage

Uses

1. Used in Materials Science:
1-Bromo-4-fluoronaphthalene is used as a starting material for the synthesis of Fluorobenzo[c]fluoren (F588435), a polycyclic aromatic hydrocarbon with extensive applications in the field of materials science. Its unique structure and properties make it a valuable component in the development of advanced materials for organic electronics, light-emitting diodes (LEDs), and solar cells.
2. Used in Organic Electronics:
In the organic electronics industry, 1-Bromo-4-fluoronaphthalene serves as a crucial precursor for the synthesis of compounds that exhibit excellent electronic properties. These synthesized materials find applications in the development of high-performance electronic devices, such as organic field-effect transistors (OFETs) and organic photovoltaics (OPVs).
3. Used in Light Emitting Diodes (LEDs):
1-Bromo-4-fluoronaphthalene is used as a key intermediate in the production of advanced materials for light-emitting diodes. The synthesized compounds based on this intermediate exhibit improved luminescent properties, leading to more efficient and longer-lasting LEDs.
4. Used in Solar Cells:
In the solar cell industry, 1-Bromo-4-fluoronaphthalene is utilized as a starting material for the synthesis of novel materials with enhanced photovoltaic properties. These materials contribute to the development of more efficient and cost-effective solar cells, paving the way for sustainable energy solutions.
5. Used in Chemical Research:
1-Bromo-4-fluoronaphthalene is also employed as a valuable compound in chemical research, particularly in the study of polycyclic aromatic hydrocarbons and their derivatives. Its unique structure and properties make it an interesting subject for exploring new synthetic routes, reaction mechanisms, and potential applications in various fields.

InChI:InChI=1/C10H6BrF/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6H

Upstream product

• 321-38-0 1-Fluoronaphthalene 
• 56-23-5 tetrachloromethane 
• 7726-95-6 bromine 

Downstream Products

• 3870-18-6 2-(4-fluoro-[1]naphthoyl)-benzoic acid 
• 1425-99-6 1-Fluor-4-o-toluoyl-naphthalin 
• 13916-99-9 4-fluoronaphthalene-1-carbonitrile 
• 1648-21-1 1-(4-Fluor-naphthyl-1)-cyclohexen-1 
• 4620-04-6 1-<4-Fluor-naphthyl-(1)>-cyclohexanol-(1) 
• 1536-34-1 p-Tolyl-<4-fluor-naphthyl-(1)>-keton 
• 1536-33-0 m-Tolyl-<4-fluor-naphthyl-(1)>-keton 
• 1827-58-3 2-(4-fluoronaphthalen-1-yl)cyclohexan-1-one 
• 182344-25-8 (4-fluoronaphthalen-1-yl)boronic acid 
• 17318-09-1 1-iodo-4-fluoronaphthalene 
• 1536-17-0 1-Carboxymethyl-2-<4-fluor-naphthyl-(1)>-cyclohexanol-(1) 
• 573-03-5 4-fluoro-1-naphthoic acid 
• 664364-14-1 2,2,2-trifluoro-1-(4-fluoro-1-naphthyl)ethanone 
• 151983-15-2 trans 1-(4-fluoro-1-naphthalenyl)-4-[4-(phenylmethyl)-1-piperazinyl]cyclohexanol 

Relevant academic research and scientific papers

4-fluoronaphthalene-1-alcohol preparation technology

The invention discloses a 4-fluoronaphthalene-1-alcohol preparation technology. The preparation technology takes 1-fluoronaphthalene as a raw material, the raw material is subjected to halogenation, boration and hydrolysis to obtain the 4-fluoronaphthalene-1-alcohol, and the overall yield can reach 60%. The technology has the advantages of low cost and easy acquisition of the raw materials, simple and easy operation of post-treatment t, high yield, and easy industrial application.

Structure-Activity Relationships of Potent, Selective Inhibitors of Neuronal Nitric Oxide Synthase Based on the 6-Phenyl-2-aminopyridine Structure

The synthesis and structure-activity relationships of a series of 6-phenyl-2-aminopyridines that potently and selectively inhibit the neuronal isoform of nitric oxide synthase (nNOS) are described. Compound 14bi from this series exhibits potent in vivo activity in harmaline-induced cGMP formation in rat cerebellum, a functional model of nNOS inhibition, and in the PCP-induced hypermotility model in the rat. These results suggest that 14bi may be a useful reagent for evaluating potential therapeutic applications of nNOS inhibitors in the central nervous system.

2-aminopyridines containing fused ring substituents

The present invention relates to 2-aminopyridine derivatives of the formula wherein G, R1 and R2 are defined as in the specification, that exhibit activity as nitric oxide synthase (NOS) inhibitors, to pharmaceutical compositions containing them and to their use in the treatment and prevention of central nervous system and other disorders.

2-aminopyridines containing fused ring substituents

The present invention relates to 2-aminopyridine derivatives of the formula I: or pharmaceutically acceptable salts thereof, whereinA and B are each independently H, or together, A and B form a ring fused to the phenyl ring, said ring being saturated or unsaturated and containing from 5 to 7 ring member atoms, where said ring member atoms may optionally comprise from 1 to 2 heteroatoms selected independently from the group consisting of N, O or S, provided that no two adjacent ring members are heteroatoms;X is oxygen or a single bond;Y is (C1-C6)alkyl;R1 is hydrogen, (C1-C6)alkyl or a (C1-C6 alkyl) group substituted with —NR2R3 wherein R2 and R3 are either selected independently from the group consisting of H, alkyl, aryl, aralkyl or tetrahydronaphthalene, wherein said aryl group or said aryl moiety of said aralkyl group is phenyl or naphthyl, said alkyl group or said alkyl moiety of said aralkyl group contains from one to six carbon atoms and is straight-chained or branched, and said aryl group, said tetrahydronaphthalene or said aryl moiety of said aralkyl group is optionally substituted with from one to three of halogen, nitro, cyano, amino, (C1-C4)alkoxy and (C1-C4)alkylamino moieties, or R2 and R3 form, together with the nitrogen to which they are attached, a heterocyclic ring, or a cyclic or bicyclic ring which is saturated or unsaturated. The compounds of the invention have the ability to inhibit the activity of nitric oxide synthases (NOS), and hence, are useful in the treatment of diseases, conditions and disorders of the central nervous system, among others.