3420-40-4

Usage

Uses

Used in Pharmaceutical Industry:
N-(3,4,5,6-TETRAHYDRO-1,3-THIAZIN-2-YLIDENE)ANILINE is used as a key intermediate for the synthesis of various pharmaceuticals due to its unique chemical structure and potential biological activities. It contributes to the development of new drugs with improved therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, N-(3,4,5,6-TETRAHYDRO-1,3-THIAZIN-2-YLIDENE)ANILINE is used as a precursor in the production of various organic compounds. Its role in creating functional materials aids in enhancing the effectiveness of agrochemical products, such as pesticides and fertilizers, ultimately benefiting agricultural practices.
Used in Organic Chemistry Research:
N-(3,4,5,6-TETRAHYDRO-1,3-THIAZIN-2-YLIDENE)ANILINE is utilized as a building block in organic chemistry for the synthesis of complex organic compounds. Its unique properties make it a valuable component in the development of novel materials and compounds with diverse applications in various industries.

Upstream product

• 7647-01-0 hydrogenchloride 
• 3420-61-9 azetidine-1-carbothioic acid anilide 
• 6276-54-6 3-chloropropylamine hydrochloride 
• 103-72-0 phenyl isothiocyanate 
• 7078-98-0 2,6-di-tert-butyl-4-benzylidene-cyclohexa-2,5-dienone 
• 29146-63-2 N-(3-hydroxypropyl)-N'-phenyl-thiourea 
• 62-53-3 aniline 
• 43009-16-1 phenyldithiocarbamic acid triethylamine salt 
• 94407-77-9 S-phenylthiocarbamoyl-thiocarbonic acid O-ethyl ester 
• 80254-04-2 N-(3-aminopropyl)-5,6,8,9-tetrahydro-7-phenyldibenzoacridinium trifluoromethanesulphonate 

Downstream Products

• 13677-25-3 3-benzoyl-2-phenylimino-[1,3]thiazinane 
• 13677-18-4 2-phenylimino-[1,3]thiazinane-3-carboxylic acid anilide 
• 13677-19-5 2-phenylimino-[1,3]thiazinane-3-carboxylic acid benzylamide 
• 13677-20-8 2-phenylimino-[1,3]thiazinane-3-carboxylic acid butylamide 
• 2933-39-3 3-Methyl-2-phenyl-imino-tetrahydro-1,3-thiazin 
• 129663-56-5 1-(5,6-Dihydro-4H-[1,3]thiazin-2-yl)-1,3,3-triphenyl-urea 
• 129663-52-1 2-[(Z)-Phenylimino]-[1,3]thiazinane-3-carboxylic acid diphenylamide 
• 129663-55-4 2-N-(N'-methyl-N'-phenylcarbamoyl)anilino-5,6-dihydro-4H-1,3-thiazine 
• 129663-51-0 2-phenylimino-3-(N-methyl-N-phenylcarbamoyl)tetrahydro-1,3-thiazine 
• 112108-92-6 3-(3-mercaptopropyl)-1-phenyl-2,4-dioxoimidazolidine 
• 554-68-7 triethylamine hydrochloride 
• 129663-48-5 1-(5,6-Dihydro-4H-[1,3]thiazin-2-yl)-1,3-diphenyl-urea 
• 34117-49-2 2,3,4-Trihydro-1,3-thiazino<3,2-a>benzimidazole 
• 3102-07-6 (5,6-dihydro-4H-[1,3]thiazin-2-yl)-methyl-phenyl-amine 

Relevant academic research and scientific papers

A Bench-Stable Vilsmeier Reagent for in situ Alcohol Activation: Synthetic Application in the Synthesis of 2-Amino-2-Thiazolines

A robust, chemoselective direct condensation/cyclization of thioureas and amino alcohols is described. Employing a bench-stable Vilsmeier reagent, methoxymethylene- N, N -dimethyliminium methyl sulfate, the selective in situ activation of alcohols is achieved with high efficiency and broad functional-group tolerance. The reversible interaction of the Vilsmeier reagent with substrate was key to the success of this activation strategy.

Synthesis of Diaryl Diazaphosphonates via 1,6-Hydrophosphonylation of p-Quinone Methides with N-Heterocyclic Phosphine-Thioureas

A mild, efficient method for the synthesis of diaryl diazaphosphonates via 1,6-hydrophosphonylation/aromatization of p-quinone methides (p-QMs) with N-heterocyclic phosphine-thioureas has been developed. This transformation proceeds without any additive or catalyst under mild reaction conditions and tolerates a wide range of p-QMs. This methodology provides a straightforward access to diaryl phosphonate derivatives in good to excellent yields (up to 99%).

Synthesis of benzimidazole-fused heterocycles by intramolecular oxidative C-N bond formation using hypervalent iodine reagents

A straightforward approach by dehydrogenative C-N coupling between aryl C-H and N-H bonds using a hypervalent iodine reagent under mild conditions offers a versatile and convenient method for synthesizing various benzimidazole-fused heterocycles. Georg Th

Selenium-containing heterocycles from isoselenocyanates: Synthesis of 1,3-selenazolidine and perhydro-1,3-selenazine derivatives

Treatment of ω-halo alkylamines 9 and 10 with aryl and alkyl isoselenocyanates 6a-g in the presence of triethylamine in dichloromethane gave the corresponding 1,3-selenazolidines 11a-g and perhydro-1,3-selenazines 12a-g, respectively, in good to excellent

Aminothiazines et aminothiazoles analogues ouverts du levamisole: synthese et approche du mode d'action nematicide

New compounds with thiazoline or dihydrothiazine rings substituted by alkylamino or arylamino groups were synthesized and screened in vitro against three Nematodes.Inhibition of fumarate-reductase activity was also evaluated.For all in vitro anti-parasitic tests, dihydrothiazines were more potent than corresponding thiazolines derivatives, however, thiazolines showed a greater inhibition of fumarate-reductase.

TRANSFORMATIONS OF PYRIDINIUMS DERIVED FROM AMINO-ALCOHOLS AND FROM DIAMINES

Pyridiniums derived from amino alcohols cyclise to ethers or rearrange to aldehydes on heating.Monopyridiniums from diamines can be acylated or converted into ureas or thioureas: these products cyclise on heating in solution to give dihydro-thiazoles, -4H-thiazines, -oxazoles, -4H-oxazines, or tetrahydro-3H-thiazepines.