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1,3-Propanedicarboxamide, also known as malonamide, is a white crystalline solid with the chemical formula C3H6N2O2. It is insoluble in water and is a derivative of malonic acid. 1,3-Propanedicarboxamide is known for its ability to form strong hydrogen bonds, which makes it useful in various applications.

3424-60-0

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3424-60-0 Usage

Uses

Used in Organic Synthesis:
1,3-Propanedicarboxamide is used as a reagent in organic synthesis for its ability to participate in various chemical reactions and form new compounds.
Used in Coordination Chemistry:
1,3-Propanedicarboxamide is used as a complexing agent in coordination chemistry due to its ability to form complexes with metal ions, which is useful in the study and development of new coordination compounds.
Used in Polymer and Resin Production:
1,3-Propanedicarboxamide is used in the production of polymers and resins, where its strong hydrogen bonding capability contributes to the formation of supramolecular structures and the properties of the final products.
Used in Pharmaceutical Industry:
1,3-Propanedicarboxamide has potential applications in the pharmaceutical industry, where its ability to form complexes with various metal ions can be utilized for the development of new drugs or drug delivery systems.
Used in Agricultural Industry:
1,3-Propanedicarboxamide also has potential applications in the agricultural industry, where its metal ion complexing ability could be employed for the development of new agrochemicals or as a component in fertilizers and pesticides.
Used as a Hydrogen-Bonding Catalyst:
Due to its strong hydrogen bonding capability, 1,3-Propanedicarboxamide is used as a hydrogen-bonding catalyst in various chemical processes, where it can facilitate reactions and improve the efficiency of the process.

Check Digit Verification of cas no

The CAS Registry Mumber 3424-60-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,4,2 and 4 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 3424-60:
(6*3)+(5*4)+(4*2)+(3*4)+(2*6)+(1*0)=70
70 % 10 = 0
So 3424-60-0 is a valid CAS Registry Number.
InChI:InChI=1/C5H10N2O2/c6-4(8)2-1-3-5(7)9/h1-3H2,(H2,6,8)(H2,7,9)

3424-60-0Relevant academic research and scientific papers

Transfer Hydration of Dinitriles to Dicarboxamides

Naka, Hiroshi,Naraoka, Asuka

supporting information, p. 1977 - 1980 (2019/10/22)

We present a robust method for double transfer hydration of dinitriles to afford diamides. The transfer hydration of 1, n -dinitriles (n = 1-6) proceeds smoothly in the presence of a palladium(II) catalyst with acetamide as a water donor, affording the corresponding diamides in moderate to high yields, without involving significant side reactions such as monohydration or cyclization. The equilibrium was shifted in the forward direction by removing coproduced acetonitrile under reduced pressure.

RhI-catalyzed hydration of organonitriles under ambient conditions

Goto, Akihiro,Endo, Kohei,Saito, Susumu

, p. 3607 - 3609 (2008/12/23)

(Chemical Presented) New scoop on scope and selectivity: The hydration of organonitriles catalyzed by a RhI(OMe) species under nearly pH-neutral and ambient conditions (25°C, 1 atm) is chemoselective and high-yielding (93 to 99%), has a broad substrate scope, and may thus be complementary to enzymatic hydration methods for the introduction of a terminal amido group (CONH2) onto a carbon chain.

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