34277-73-1Relevant academic research and scientific papers
Synthesis of acyl carbamates via four component Pd-catalyzed carbonylative coupling of aryl halides, potassium cyanate, and alcohols
Yin, Hongfei,De Almeida, Angelina M.,De Almeida, Mauro V.,Lindhardt, Anders T.,Skrydstrup, Troels
, p. 1248 - 1251 (2015)
A simple and mild method is demonstrated for assembling acyl carbamates through a base-free four-component Pd-catalyzed carbonylation of aryl halides in the presence of potassium cyanate and alcohols in a two-chamber system. This approach produces a wide range of aryl acyl carbamates in good to excellent yields from the corresponding aryl bromides or iodides with near-stoichiometric carbon monoxide. In addition, the method can be extended to the synthesis of primary amides thereby expanding the usefulness of cyanate as an ammonia equivalent.
Enabling the facile conversion of acyl hydrazides into: N -acyl carbamates via metal-free ionic-based rupture of the N-N linkage
Shamsabadi, André,Ren, Jack,Chudasama, Vijay
, p. 27608 - 27611 (2017)
Herein we report the one-pot transformation of readily synthesised/easily accessed acyl hydrazides into N-acyl carbamates via an alkylation-elimination reaction sequence. A range of N-acyl carbamates are prepared in consistent yields, including those featuring protecting groups and having alkyl & aryl N-acyl functionality. The reaction conditions also tolerate a wide variety of sensitive functional groups.
Reaction of TPP-azodicarboxylate zwitterions and aryl aldehydes: unprecedented synthesis of acyl carbamates
Nair, Vijay,Mathew, Smitha C.,Biju,Suresh
, p. 9018 - 9020 (2008/03/18)
An efficient synthesis of acyl carbamates from aryl aldehydes by the reaction of triphenylphosphine and dialkyl azoesters is described.
