34372-24-2

Basic information

• Product Name: [2-(benzylsulfanyl)ethyl]benzene
• CAS NO: 34372-24-2
• Molecular Formula: C₁₅H₁₆S
• Molecular Weight: 228.3525
• Mol File: 34372-24-2.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 353.1°C at 760 mmHg
• Flash Point: 161.1°C
• Density: 1.069g/cm³
• Vapor Pressure: 7.46E-05mmHg at 25°C
• Refractive Index: 1.599
• CAS DataBase Reference: [2-(benzylsulfanyl)ethyl]benzene(CAS DataBase Reference)
• NIST Chemistry Reference: [2-(benzylsulfanyl)ethyl]benzene(34372-24-2)
• EPA Substance Registry System: [2-(benzylsulfanyl)ethyl]benzene(34372-24-2)

Safety Data

• Hazardous Substances Data: 34372-24-2(Hazardous Substances Data)

Usage

General Description

"[2-(benzylsulfanyl)ethyl]benzene" is a chemical compound with the molecular formula C16H18S. It is a benzene derivative with a benzylsulfanyl group attached to an ethyl chain, which in turn is attached to another benzene ring. [2-(benzylsulfanyl)ethyl]benzene is commonly used as a starting material in organic synthesis to create various pharmaceuticals, pesticides, and other chemical products. It has a role as a fragrance and a flavoring agent. The compound is typically synthesized through a series of organic reactions involving benzyl chloride, sodium sulfide, and other reagents. Its structure and properties make it useful for a wide range of industrial and commercial applications.

Upstream product

• 3492-64-6 sodium benzylmercaptide 
• 103-63-9 1-phenyl-2-bromoethane 
• 60-12-8 2-phenylethanol 
• 100-53-8 phenylmethanethiol 
• 4410-99-5 2-mercaptophenylethane 
• 1207372-94-8 benzyl 2-[2-(4-nitrophenyl)ethynyl]benzoate 
• 1207372-95-9 benzyl 2-{2-[4-(trifluoromethyl)phenyl]ethynyl}benzoate 
• 1207372-96-0 o-[2-(4-methoxyphenyl)ethynyl]benzoic acid benzyl ester 
• 1207372-97-1 benzyl 2-[2-(2,4-dimethoxyphenyl)ethynyl]benzoate 
• 3558-60-9 1-methoxy-2-phenylethane 
• 100-51-6 benzyl alcohol 
• 100-42-5 styrene 
• 78-67-1 2,2'-azobis(isobutyronitrile) 
• 150-60-7 dibenzyl disulphide 

Downstream Products

• 67399-12-6 (2-(benzylsulfonyl)ethyl)benzene 
• 5654-72-8 2-phenylethyl thiocyanate 
• 90923-56-1 (2-phenylethylthio)acetonitrile 
• 4410-99-5 2-mercaptophenylethane 
• 4025-71-2 2-phenylethylsulfonyl chloride 

Relevant articles and documents

Photogeneration of thiyl radicals using metal-halide perovskite for highly efficient synthesis of thioethers

Recently, the use of metal-halide perovskite (MHP) for photoinduced organics transformation has attracted much attention. We report herein the development of photoinduced thiol-ene reaction using inorganic MHP of CsPbBr3 nanocrystal that is visible light-responsive, easy-to-prepare, and cost-effective. Under blue light-emitting diode (LED), a series of thiol substrates are demonstrated to be highly efficient reaction partners to couple with alkenes tolerated with various functional groups, affording diverse thioethers containing C–S bonds. The CsPbBr3-mediated thiol-ene reaction is characterized by high efficiency, broad substrate applicability, excellent yields, and mild conditions. Mechanism investigation shows that the visible light-excited CsPbBr3 induces the generation of thiyl radicals via hole oxidation to initiate the reaction, followed by redox neutral pathway and/or chain transfer pathway to accomplish thiol–olefin coupling. It is notable that CsPbBr3 exhibits advanced thiol-ene performance than that using MHP analogs and others. The work presents a new exploration of MHP-mediated transformation and shows great potential of MHPs for radical chemistry.

Zinc-catalyzed regioselective addition of alkyl thiols to alkenes via anion or radical reactions

Zn-catalyzed reactions of alkenes with alkyl thiols could afford alkyl sulfides regioselectively. When the ZnI2- catalyzed hydrothiolation of alkenes was achieved using alkyl thiols at 100 °C, Markovnikov-type alkyl sulfides were obtained in excellent yields without the formation of linear products. To the contrary, Zn(OAc)2- catalyzed reaction gave rise only to anti-Markovnikov-type products regioselectively. The reaction proceeded via a radical process.

Zirconium-catalysed direct substitution of alcohols: enhancing the selectivity by kinetic analysis

Kinetic analysis was used as a tool for rational optimization of a catalytic, direct substitution of alcohols to enable the selective formation of unsymmetrical ethers, thioethers, and Friedel-Crafts alkylation products using a moisture-tolerant and commercially available zirconium complex (2 to 8 mol%). Operating in air and in the absence of dehydration techniques, the protocol furnished a variety of products in high yields, including glycosylated alcohols and sterically hindered ethers. In addition, the kinetic studies provided mechanistic insight into the network of parallel transformations that take place in the reaction, and helped to elucidate the nature of the operating catalyst.