344357-19-3

Upstream product

• 125261-01-0 2-(2-phenyl-1,3-dioxolan-2-yl)acetaldehyde 
• 202846-65-9 (3S,4R)-3-methoxymethyloxy-4-methyl-4-vinyl-γ-butyrolactone 
• 5764-85-2 Ethyl 3-hydroxy-3-phenylpropanoate 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 73840-71-8 diethyl (2S,3R)-(+)-2-hydroxy-3-methylsuccinate 
• 344357-31-9 (3S,4S)-3-methoxymethyloxy-4-methyl-4-[2-(2-nitrophenyl)seleno]-γ-butyrolactone 
• 344357-29-5 (2S,3R)-5-benzyloxy-3-ethoxycarbonyl-2-hydroxy-3-methylpentanoic acid 
• 202846-62-6 (2R,3S)-2-(2-Benzyloxy-ethyl)-3-hydroxy-2-methyl-succinic acid diethyl ester 
• 344357-30-8 (3S,4S)-4-(2-benzyloxyethyl)-3-methoxymethyloxy-4-methyl-γ-butyrolactone 
• 202846-63-7 (3S,4S)-4-(2-benzyloxyethyl)-3-hydroxy-4-methyl-γ-butyrolactone 
• 202846-64-8 (3S,4S)-4-(2-hydroxyethyl)-3-methoxymethyloxy-4-methyl-γ-butyrolactone 
• 27773-03-1 ethyl 3,3-(ethylenedioxy)-3-phenylpropanoate 

Downstream Products

• 344357-25-1 (3R,4R)-3-[3',3'-(ethylenedioxy)-3'-phenylpropanoyl]-3-methoxymethyloxy-4-methyl-4-vinyl-γ-butyrolactone 
• 344357-20-6 (3S,4R)-3-[3',3'-(ethylenedioxy)-3'-phenylpropanoyl]-3-methoxymethyloxy-4-methyl-4-vinyl-γ-butyrolactone 
• 165170-94-5 (5S,9S)-9-methyl-2-phenyl-9-vinyl-1,7-dioxaspiro[4.4]non-2-ene-4,6-dione 

Relevant academic research and scientific papers

Synthesis of Hyperolactones A and C

Hyperolactones A (1) and C (3) have been synthesized starting from (S)-malic acid by a straightforward route. The unique spirolactone skeleton was efficiently constructed by one-pot reaction as a key step. The absolute stereochemistry of hyperolactones was unambiguously established by this synthesis.