344361-90-6

Basic information

• Product Name: Ethyl 4-Methyl-2-(Methylthio)-6-oxo-1,6-dihydropyriMidine-5-carboxylate
• Synonyms: Ethyl 4-Methyl-2-(Methylthio)-6-oxo-1,6-dihydropyriMidine-5-carboxylate;ethyl 4-methyl-2-(methylsulfanyl)-6-oxo-1,6-dihydropyrimidine-5-carboxylate
• CAS NO: 344361-90-6
• Molecular Formula: C₉H₁₂N₂O₃S
• Molecular Weight: 228.26818
• Mol File: 344361-90-6.mol

Chemical Properties

• Boiling Point: 342.1±52.0 °C(Predicted)
• Appearance: /
• Density: 1.33±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 6.92±0.50(Predicted)
• CAS DataBase Reference: Ethyl 4-Methyl-2-(Methylthio)-6-oxo-1,6-dihydropyriMidine-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 4-Methyl-2-(Methylthio)-6-oxo-1,6-dihydropyriMidine-5-carboxylate(344361-90-6)
• EPA Substance Registry System: Ethyl 4-Methyl-2-(Methylthio)-6-oxo-1,6-dihydropyriMidine-5-carboxylate(344361-90-6)

Safety Data

• Hazardous Substances Data: 344361-90-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Ethyl 4-Methyl-2-(Methylthio)-6-oxo-1,6-dihydropyriMidine-5-carboxylate is used as a chemical intermediate in the synthesis of various pharmaceutical compounds. Its unique structural features, including the dihydropyrimidine core, ethyl ester, methylthio, and carboxylate groups, contribute to its potential applications in the development of new drugs with therapeutic benefits.
Used in Medicinal Chemistry Research:
As a dihydropyrimidine derivative, Ethyl 4-Methyl-2-(Methylthio)-6-oxo-1,6-dihydropyriMidine-5-carboxylate serves as a valuable starting material for medicinal chemistry research. Researchers can modify its structure to explore its potential as a lead compound for the treatment of various diseases and disorders. Its pharmacological properties and chemical reactivity make it an attractive candidate for further investigation and optimization.
Used in Organic Synthesis:
Ethyl 4-Methyl-2-(Methylthio)-6-oxo-1,6-dihydropyriMidine-5-carboxylate can also be employed as an intermediate in organic synthesis for the preparation of other complex organic molecules. Its functional groups, such as the ethyl ester and carboxylate, can be utilized in various synthetic transformations, enabling the synthesis of a wide range of compounds with diverse applications.

Upstream product

• 36239-09-5 ethyl chlorocarbonylacetate 
• 583878-41-5 ethyl 4-methyl-2-(methylsulfanyl)-6-oxo-1,4,5,6-tetrahydro-5-pyrimidinecarboxylate 
• 769911-78-6 1-(1-dimethylamino-ethylidene)-2-methyl-isothiourea 
• 344361-87-1 ({[1-(dimethylamino)ethylidene]amino}(methylsulfanyl)methylidene)azanium iodide 
• 1462-12-0 diethyl ethylidenemalonate 
• 2986-19-8 carbamimidothioic acid methyl ester 

Downstream Products

• 869219-81-8 4-cycloheptylamino-6-methyl-2-methylsulfanyl-pyrimidin-5-carbaldehyde 
• 1300607-40-2 4-(3,5-dimethoxyphenylamino)-2-(4-hydroxy-4-(hydroxymethyl)piperidin-1-yl)pyrido[4,3-d]pyrimidin-5(6H)-one 
• 1300611-21-5 (E)-ethyl 4-(2-(dimethylamino)vinyl)-6-(4-methoxyphenyl)-2-(methylthio)pyrimidine-5-carboxylate 
• 1236204-32-2 ethyl 4-(4-methoxyphenyl)-6-methyl-2-(methylthio)pyrimidine-5-carboxylate 
• 1300607-38-8 4-(3,5-dimethoxyphenylamino)-2-(4-hydroxypiperidin-1-yl)pyrido[4,3-d]pyrimidin-5(6H)-one 
• 1300609-69-1 4-(3,5-dimethoxyphenylamino)-2-(methylthio)pyrido[4,3-d]pyrimidin-5(6H)-one 
• 1300609-68-0 (E)-ethyl 4-(3,5-dimethoxyphenylamino)-6-(2-(dimethylamino)vinyl)-2-(methylthio)pyrimidine-5-carboxylate 
• 1300609-67-9 ethyl 4-(3,5-dimethoxyphenylamino)-6-methyl-2-(methylthio)pyrimidine-5-carboxylate 
• 1312691-89-6 tert-Butyl (1S,2R)-2-(6-(2,4-dimethoxybenzyl)-4-(1,5-dimethyl-1H-pyrazol-4-yl)-5-oxo-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-2-ylamino)cyclohexylcarbamate 
• 1312691-88-5 ethyl 2-((1R,2S)-2-(tert-butoxycarbonylamino)cyclohexylamino)-4-(1,5-dimethyl-1H-pyrazol-4-yl)-6-methylpyrimidine-5-carboxylate 
• 583878-42-6 ethyl 4-chloro-6-methyl-2-(methylthio)pyrimidine-5-carboxylate 
• 934493-76-2 voxtalisib 
• 934493-79-5 8-ethyl-4-methyl-2-(methylthio)pyrido[2,3-d]pyrimidin-7(8H)-one 

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