345-71-1

Basic information

• Product Name: 3,4''-DIFLUOROBENZOPHENONE
• Synonyms: (3-Fluorophenyl)(4-fluorophenyl)methanone
• CAS NO: 345-71-1
• Molecular Formula: C₁₃H₈F₂O
• Molecular Weight: 218.201
• Mol File: 345-71-1.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3,4''-DIFLUOROBENZOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4''-DIFLUOROBENZOPHENONE(345-71-1)
• EPA Substance Registry System: 3,4''-DIFLUOROBENZOPHENONE(345-71-1)

Safety Data

• Hazardous Substances Data: 345-71-1(Hazardous Substances Data)

Usage

General Description

3,4''-Difluorobenzophenone is a chemical compound with the molecular formula C13H8F2O. It is a white crystalline solid that is used in various industrial applications, including as an intermediate in the production of pharmaceuticals, dyes, and other organic compounds. This chemical is also utilized as a photo-initiator in the formulation of UV-curable coatings and inks. Additionally, 3,4''-Difluorobenzophenone has potential applications in the field of materials science, such as in the development of advanced polymers and materials with specific optical properties. However, it is important to handle this chemical with care, as it may cause skin and eye irritation, and is harmful if swallowed or inhaled. Proper safety precautions and handling procedures should be followed when working with 3,4''-Difluorobenzophenone.

Upstream product

• 7613-39-0 1,1,1-trichloro-2-(3-fluoro-phenyl)-2-(4-fluoro-phenyl)-ethane 
• 462-06-6 fluorobenzene 
• 403-43-0 4-fluorobenzoyl chloride 
• 226260-01-1 3-fluoro-N-methoxy-N-methylbenzamide 
• 1493-23-8 (4-fluorophenyl)lithium 
• 14101-14-5 (4-fluorophenyl)trimethyltin 
• 768-35-4 3-fluorophenylboronic acid 
• 1121-86-4 1-Fluoro-3-iodobenzene 
• 50978-45-5 3-oxobenzo[d]isothiazole-2(3H)-carbaldehyde 1,1-dioxide 
• 1765-93-1 4-fluoroboronic acid 

Downstream Products

• 93765-58-3 (3-Fluoro-phenyl)-(4-fluoro-phenyl)-pyrimidin-5-yl-methanol 

Relevant articles and documents

Mechanochemical Solvent-Free Suzuki–Miyaura Cross-Coupling of Amides via Highly Chemoselective N?C Cleavage

Although cross-coupling reactions of amides by selective N?C cleavage are one of the most powerful and burgeoning areas in organic synthesis due to the ubiquity of amide bonds, the development of mechanochemical, solid-state methods remains a major challe

A Rapid Injection NMR Study of the Reaction of Organolithium Reagents with Esters, Amides, and Ketones

Unexpectedly high rates of reaction between alkyllithium reagents and amides, compared to esters and ketones, were observed by Rapid Inject NMR and competition experiments. Spectroscopic investigations with 4-fluorophenyllithium (ArLi, mixture of monomer and dimer in THF) and a benzoate ester identified two reactive intermediates, a homodimer of the tetrahedral intermediate, stable below -100°C, and a mixed dimer with ArLi. Direct formation of dimers suggested that the ArLi dimer may be the reactive aggregate rather than the usually more reactive monomer. In contrast, RINMR experiments with ketones demonstrated that the ArLi monomer was the reactive species. (Chemical Equation Presented).

Preparation process of fluorine substituted aromatic compound

A preparation process of a fluorine substituted aromatic compound comprising reacting an alkali metal or alkali earth metal salt of an aromatic compound having a hydroxy group with an organic fluorinating agent is disclosed. As a representative fluorinating agent, a bis-dialkylamino-difluoromethane compound, for example, 2,2′-difluoro-1,3-dimethylimidazolidine, is exemplified. According to the process, an industrially useful fluorinated aromatic compound, for example, a fluorobenzene, a fluorine substituted benzophenone, a fluorine substituted diarylsulfone can be prepared with ease in economy without specific equipment.