3481-15-0Relevant articles and documents
Regeneration of NAD(P)H Using Glucose 6-Sulfate and Glucose-6-phosphate Dehydrogenase
Wong, Chi-Huey,Gordon, Jennifer,Cooney, Charles L.,Whitesides, George M.
, p. 4676 - 4679 (1981)
Glucose 6-sulfate and glucose-6-phosphate dehydrogenase have been used for NAD(P)H cofactor regeneration in preparations of (S)-benzyl-α-d1 alcohol and threo-DS(+)-isocitrate (0.1-mol scale).The reduced nicotinamide cofactors are mor
Method for synthesizing chiral deuterated primary alcohol
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Paragraph 0031-0036; 0160-0173, (2021/05/29)
The invention discloses a method for synthesizing chiral deuterated primary alcohol. The method comprises the following step: reacting an aldehyde compound in an aprotic organic solvent at room temperature under the action of a chiral cobalt catalyst by t
Imidazopyrazinone compound as well as preparation method and application thereof
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Paragraph 0070; 0074-0076, (2021/10/11)
The invention provides an imidazopyrazinone compound as well as a preparation method and application thereof. The imidazopyrazinone compound structure has the structure shown I, and R. 1 Is phenyl. R2 In the benzyl group, and the compound has at least one D substituent, the D substituent is at R. 1 And/or R2 . The compound has excellent luminescence performance, can be used as a substrate of NanoLuc luminescent system, and is applied to detection and drug detection of luciferase.
Aryl-Nickel-Catalyzed Benzylic Dehydrogenation of Electron-Deficient Heteroarenes
Zhang, Pengpeng,Huang, David,Newhouse, Timothy R.
supporting information, p. 1757 - 1762 (2020/02/04)
This manuscript describes the first practical benzylic dehydrogenation of electron-deficient heteroarenes, including pyridines, pyrazines, pyrimidines, pyridazines, and triazines. This transformation allows for the efficient benzylic oxidation of heteroarenes to afford heterocyclic styrenes by the action of nickel catalysis paired with an unconventional bromothiophene oxidant.