3481-20-7

Basic information

• Product Name: 2,3,5,6-TETRACHLOROANILINE
• Synonyms: Aniline, 2,3,5,6-tetrachloro-;2,3,5,6-TETRACHLOROANILINE;2,3,5,6-TETRACHLOROANILINE PESTANAL,250;2 3 5 6-TETRACHLOROANILINE 97%;2,3,5,6-TETRACHLOROBENZENAMINE;1-AMINO-2,3,5,6-TETRACHLOROBENZENE
• CAS NO: 3481-20-7
• Molecular Formula: C₆H₃Cl₄N
• Molecular Weight: 230.91
• EINECS: 222-461-9
• Product Categories: Alpha sort;Pesticides&Metabolites;Q-ZAlphabetic;TA - TE
• Mol File: 3481-20-7.mol
• Article Data: 1

Chemical Properties

• Melting Point: 106 °C
• Boiling Point: 299.1°Cat760mmHg
• Flash Point: 134.7°C
• Appearance: /
• Density: 1.655g/cm³
• Vapor Pressure: 0.00122mmHg at 25°C
• Refractive Index: 1.636
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: -1.40±0.10(Predicted)
• CAS DataBase Reference: 2,3,5,6-TETRACHLOROANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,5,6-TETRACHLOROANILINE(3481-20-7)
• EPA Substance Registry System: 2,3,5,6-TETRACHLOROANILINE(3481-20-7)

Safety Data

• Hazard Codes: T
• Statements: 23/24/25-33
• Safety Statements: 36/37-45
• RIDADR: 2811
• HazardClass: 9
• PackingGroup: III
• Hazardous Substances Data: 3481-20-7(Hazardous Substances Data)

Usage

Purification Methods

Crystallise it from EtOH. The acetyl derivative has m 213-214o (from EtOH). [Beilstein 12 II 340, 12 III 1414, 12 IV 1287.]

InChI:InChI=1/C6H3Cl4N/c7-2-1-3(8)5(10)6(11)4(2)9/h1H,11H2

Upstream product

• 117-18-0 2,3,5,6-Tetrachloronitrobenzene 
• 7664-41-7 ammonia 
• 7647-01-0 hydrogenchloride 
• 69733-49-9 acetic acid-(2,3,5,6-tetrachloro-N-nitro-anilide) 
• 10034-85-2 hydrogen iodide 

Downstream Products

• 99515-60-3 N,N'-bis-(2,3,5,6-tetrachloro-phenyl)-urea 
• 52663-75-9 2,2',3,3',4',5,5',6-octachlorobiphenyl 
• 52663-77-1 2,2',3,3',4,5,5',6,6'-nonachlorobiphenyl 
• 68671-85-2 O-Ethyl-S-2,3,5,6-tetrachlorophenylxanthate 
• 714958-70-0 N-(2,3,5,6-tetrachloro-phenyl)-oxalamic acid 
• 81081-98-3 bis-(2,3,5,6-tetrachloro-phenyl)-disulfide 
• 4707-16-8 2,3,5,6-Tetrachlorobenzenethiol 
• 192770-46-0 2,3-Bis(2,3,5,6-tetrachloroanilino)-1,4-difluoroanthraquinone 
• 40398-02-5 2,3,5,6-tetrachlorophenyl isocyanate 
• 64186-91-0 4-bromo-2,3,5,6-tetrachloroaniline 
• 4901-51-3 2,3,4,5-tetrachlorophenol 
• 6936-40-9 2,3,5,6-tetrachloroanisole 
• 13074-99-2 1,2,4,5-tetrachloro-3,6-dibromobenzene 
• 69733-52-4 2,3,5,6-tetrachloro-N-methyl-N-nitro-aniline 

Relevant articles and documents

Synthesis of dioxin-like monofluorinated PCBs: for the use as internal standards for PCB analysis

Monofluorinated polychlorinated biphenyls (fluoro-PCBs) have been prepared using the Suzuki-coupling, for use as analytical standards for PCB measurements. Seven of these fluoro-PCBs are analogues of the dioxin-like PCBs, listed by the WHO as the most toxic PCB congeners. Four highly chlorinated fluoro-PCBs have been prepared by Suzuki-coupling of 2,3,5,6-tetrachloro-bromoaniline with various substituted arylboronic acids. The resulting amino-fluoro-PCBs are chlorinated using the Sandmeyer reaction or deaminated to yield tetra-, penta- and hexa-chlorinated fluoro-PCBs. The fluoro-PCBs elute just before the corresponding PCBs in the GC chromatogram, which strongly indicates their potential as analytical standards.