34868-16-1Relevant articles and documents
Cascade intramolecular Prins/Friedel–Crafts cyclization for the synthesis of 4-aryltetralin-2-ols and 5-aryltetrahydro-5H-benzo[7]annulen-7-ols
Meng, Shuyu,Wang, Quanrui,Zheng, Jie
, p. 1481 - 1489 (2021/07/02)
The treatment of 2-(2-vinylphenyl)acetaldehydes or 3-(2-vinylphenyl)propanals with BF3·Et2O results in an intramolecular Prins reaction affording intermediary benzyl carbenium ions, which are then trapped by a variety of electron-ric
Highly Selective Synthesis of Tetrahydronaphthaleno[60]fullerenes via Fullerene-Cation-Mediated Intramolecular Cyclization
Yang, Xiao-Yu,Lin, Hao-Sheng,Matsuo, Yutaka
, p. 16314 - 16322 (2019/12/25)
A high-yielding protocol to construct six-membered carbon rings on fullerene is presented. This methodology with in situ fullerene-cation-mediated intramolecular cyclization provides high selectivity and efficient access to six-membered tetrahydronaphthal
ANTI-HCMV COMPOSITIONS AND METHODS
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Page/Page column 81; 82, (2016/06/06)
This document relates to compounds useful as agents for preventing or treating human cytomegalovirus (HCMV) infections.
Synthesis of alcohols via a rhodium-catalyzed hydroformylation-reduction sequence using tertiary bidentate amine ligands
Cheung, Lawrence L. W.,Vasapollo, Giuseppe,Alper, Howard
supporting information; experimental part, p. 2019 - 2022 (2012/09/22)
The synthesis of alcohols from aromatic olefins is described using a rhodium-catalyzed hydroformylation-reduction sequence with the assistance of a tertiary diamine ligand. The alcohols are produced in excellent branched to linear ratios and in good to excellent isolated yields. In all cases no aldehyde product, from hydroformylation, or alkyl product, from olefin reduction, was detected. Copyright
BORON-CONTAINING SMALL MOLECULES AS ANTI-PROTOZOAL AGENT
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Page/Page column 97, (2011/10/10)
This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent. The compounds are of the formula, wherein Y' is a halogen, Y is halosubstituted alkyl, or a salt thereof.
Lipase-mediated resolution of substituted 2-aryl-propanols: Application to the enantioselective synthesis of phenolic sesquiterpenes
Serra, Stefano
, p. 619 - 628 (2011/07/08)
A comprehensive study of the lipase-mediated resolution of substituted 2-aryl-propanols is reported. The latter alcohols were submitted to the irreversible acetylation catalyzed either by PPL, CRL, or lipase PS. The enantioselectivity of these transformations was dependent on the type of lipase used. The type of substituents and particularly their position on the aromatic ring strongly affected the selectivity of the reaction. The experiments described prove that PPL is the more versatile lipase catalyzing the acetylation with an enantiomeric ratio (E) value that ranges from 1 up to 144, depending on the substrate used. Conversely, the same transformations were catalyzed by CRL and lipase PS with an enantiomeric ratio value, which is always less than 5. The remarkable behavior of PPL was exploited in the large scale resolution of some substituted 2-aryl-propanols whose enantiomeric forms are relevant building blocks in the enantioselective synthesis of phenolic sesquiterpenes. By these means, the synthesis of (S)-turmeronol B and the formal syntheses of (R)-curcumene, (R)-curcuphenol, (R)-xanthorrhizol, and (R)-curcuhydroquinone were accomplished.
