34889-55-9Relevant academic research and scientific papers
Cycloaddition of CO2 to challenging N-tosyl aziridines using a halogen-free niobium complex: Catalytic activity and mechanistic insights
Arayachukiat, Sunatda,Yingcharoen, Prapussorn,Vummaleti, Sai V.C.,Cavallo, Luigi,Poater, Albert,D'Elia, Valerio
, p. 280 - 285 (2017/11/15)
An efficient and facile approach to the regioselective synthesis of N-tosyloxazolidinones from the corresponding N-tosylaziridines and CO2 was developed using dual catalytic systems involving an early transition metal coordination compound as a Lewis acid and a nucleophilic cocatalyst. Among the screened Lewis acids, halogen-free niobium pentaethoxide (Nb(OEt)5) displayed the best catalytic activity when used in the presence of tetrabutylammonium iodide (TBAI). Systematic DFT calculations, supported by catalytic experiments, demonstrate that CO2 insertion is the rate determining step for this process and it is highly dependent on the steric hindrance at the niobium center.
Facile synthesis of oxazolidinones catalyzed by n-Bu4NBr 3/n-Bu4NBr directly from olefins, chloramine-T and carbon dioxide
Kong, De-Lin,He, Liang-Nian,Wang, Jin-Quan
experimental part, p. 992 - 995 (2010/11/16)
A binary catalyst systemcomposed of n-Bu4NBr3/n-Bu4NBrwas developed for facile synthesis of 5-substituted 2-oxazolidinoneswith perfect regioselectivity in a single operation directly fromolefins, chloramine-T and CO2. The choice of efficient binary catalysts for two steps, i.e. aziridination and cycloaddition, and the optimization of reaction condition are keys to the one-pot synthesis of 5-substituted 2-oxazolidinones. A possiblemechanismfor the present one-pot synthesis of oxazolidinones was also proposed.
A mild synthesis of13C-methanol
Fr?hlich, J?rg,Berger, Stefan
, p. 2522 - 2524 (2007/10/03)
The formation of oxazolidinon-2-ones from amino alcohols and carbon dioxide is well known. Until now it was not possible to reduce the fixed carbon dioxide to any basic chemical like formaldehyde or methanol, only the less interesting N-methyl compounds w
Ring-Closure Reactions through Intramolecular Displacement of the Phenylselenonyl Group by Nitrogen Nucleophiles: A New Stereospecific Synthesis of N-Tosyl and N-Benzoyl-1,3-oxazolidin-2-ones from β-Hydroxyalkyl Phenyl Selenides
Tiecco, Marcello,Testaferri, Lorenzo,Temperini, Andrea,Bagnoli, Luana,Marini, Francesca,Santi, Claudio
, p. 1752 - 1764 (2007/10/03)
A new and convenient method for the stereospecific synthesis of variously substituted 1,3-oxazolidin-2-ones from the easily available β-hydroxyalkyl phenyl selenides is presented. After transformation into the N-tosyl or N-benzoyl carbamates, the selenide
