34900-45-3

Basic information

• Product Name: 1H-Pyrrole-2,5-dione, 3-phenyl-
• Synonyms: 3-phenyl-pyrrole-2,5-dione;1H-Pyrrole-2,5-dione,3-phenyl;phenylenedimaleimide;o-phenylenedimaleimide;3-Phenyl-pyrrol-2,5-dion
• CAS NO: 34900-45-3
• Molecular Formula: C10H7NO2
• Molecular Weight: 173.171
• Mol File: 34900-45-3.mol
• Article Data: 5

Chemical Properties

• Melting Point: 167-168 °C(Solv: dichloromethane (75-09-2); ligroine (8032-32-4))
• Boiling Point: 362.3±31.0 °C(Predicted)
• Density: 1.299±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1H-Pyrrole-2,5-dione, 3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole-2,5-dione, 3-phenyl-(34900-45-3)
• EPA Substance Registry System: 1H-Pyrrole-2,5-dione, 3-phenyl-(34900-45-3)

Safety Data

• Hazardous Substances Data: 34900-45-3(Hazardous Substances Data)

Usage

Molecular Weight

173.19 g/mol

Structure

A pyrrolidine-2,5-dione derivative with a phenyl substituent at the 3-position.

Applications

Versatile in organic synthesis and pharmaceutical research, studied for potential therapeutic effects in the treatment of various diseases and conditions.

Importance

A key intermediate in the synthesis of various organic compounds, used as a building block in the production of pharmaceuticals and other chemicals.

Upstream product

• 541-59-3 maleiimide 
• 100-34-5 benzene diazonium chloride 
• 7732-18-5 water 
• 67-64-1 acetone 
• 80-17-1 benzenesufonyl hydrazide 
• 98-09-9 benzenesulfonyl chloride 
• 553-54-8 lithium benzoate 
• 62-53-3 aniline 
• 36122-35-7 2-phenylmaleic anhydride 

Downstream Products

• 257865-87-5 N-(3,5-dinitrophenyl)-methyl-α-phenylmaleimide 
• 142-82-5 n-heptane 
• 940055-66-3 3-(2-aminobenzylamino)-4-phenylpyrrolidine-2,5-dione 
• 940055-65-2 3-(2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-4-phenylpyrrolidine-2,5-dione 
• 114531-21-4 (S)-3-phenyl-2,5-pyrrolidinedione 
• 114531-20-3 (R)-3-phenyl-2,5-pyrrolidinedione 

Relevant articles and documents

Approach to the Synthesis of Unsymmetrical/Symmetrical Maleimides via Desulfitative Arylation at Different Temperatures

New routes toward selective synthesis of both mono-and diaryl maleimides have been innovated. The mere requirement to this end is through the increase of temperature. The method works effectively for maleic anhydride and maleic acid as well. Also, the fir

Weak Coordinating Carboxylate Directed Rhodium(III)-Catalyzed C-H Activation: Switchable Decarboxylative Heck-Type and [4 + 1] Annulation Reactions with Maleimides

A weakly coordinating carboxylate directing group assisted C-H activation with maleimides leading to novel and switchable decarboxylative Heck-type and [4 + 1] annulation products catalyzed by Rh(III) has been reported. In these reactions, solvents play a

Pyrrolidine(thi)ones Substituted by Heterocyclic Substituents in The 3-Position

Pyrrolidine(thi)one compounds substituted by heterocyclic substituents in the 3-position, their preparation and use in pharmaceutical compositions, in particular as immunomodulators for treatment and/or inhibition of inflammatory and autoimmune diseases and haematological-oncological diseases.