34904-87-5

Basic information

• Product Name: 1-Butanone, 4-methoxy-1-phenyl-
• CAS NO: 34904-87-5
• Molecular Formula: C11H14O2
• Molecular Weight: 178.231
• Mol File: 34904-87-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-Butanone, 4-methoxy-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Butanone, 4-methoxy-1-phenyl-(34904-87-5)
• EPA Substance Registry System: 1-Butanone, 4-methoxy-1-phenyl-(34904-87-5)

Safety Data

• Hazardous Substances Data: 34904-87-5(Hazardous Substances Data)

Usage

Physical state

Clear, colorless liquid

Odor

Sweet

Usage

Flavoring agent in the food industry

Usage

Intermediate in pharmaceutical production

Usage

Reagent in organic synthesis

Toxicity

Moderately toxic

Health effects

Skin, eye, and respiratory system irritation

Flammability

Flammable

Safety precaution

Handle with care in well-ventilated areas

Upstream product

• 98-86-2 acetophenone 
• 109-85-3 2-methoxyethylamine 
• 109-86-4 2-methoxy-ethanol 
• 3481-02-5 cyclopropyl phenyl ketone 
• 100-52-7 benzaldehyde 
• 38624-41-8 4-methoxy-1-phenylbutan-1-ol 
• 560095-49-0 (1-phenyl-2-propen-1-yl)pentamethyl phosphoric triamide 
• 560095-46-7 C₁₃H₂₂N₃OP 
• 560095-43-4 (1-phenyl-2-propen-1-yl)amidophosphoric dichloride 
• 4393-21-9 1-(phenyl)allylamine 
• 560095-70-7 (4-methoxy-1-phenyl-1-buten-1-yl)pentamethyl phosphoric triamide 
• 3308-98-3 2-(3-chloropropyl)-2-phenyl-[1,3]dioxolane 
• 124-41-4 sodium methylate 
• 71434-05-4 Di-tert-butyl(2-Methoxyethyl)malonat 

Downstream Products

• 88241-54-7 (E)-7-methoxy-4-phenylhept-2-en-4-ol 
• 88241-52-5 7-methoxy-4-phenylhepta-2,3-diene 
• 34903-03-2 C₁₁H₁₄O₂ 
• 88241-42-3 7-methoxy-4-phenylhept-2-yn-4-ol 
• 71433-95-9 C₁₁H₁₃⁽²⁾H₂ClO 
• 71433-94-8 C₁₁H₁₄⁽²⁾HClO 
• 71433-93-7 (1-Chloro-4-methoxy-butyl)-benzene 
• 38624-41-8 4-methoxy-1-phenylbutan-1-ol 

Relevant articles and documents

Cyclometalated Ruthenium Pincer Complexes as Catalysts for the α-Alkylation of Ketones with Alcohols

Ruthenium PNP pincer complexes bearing supplementary cyclometalated C,N-bound ligands have been prepared and fully characterized for the first time. By replacing CO and H? as ancillary ligands in such complexes, additional electronic and steric modifications of this topical class of catalysts are possible. The advantages of the new catalysts are demonstrated in the general α-alkylation of ketones with alcohols following a hydrogen autotransfer protocol. Herein, various aliphatic and benzylic alcohols were applied as green alkylating agents for ketones bearing aromatic, heteroaromatic or aliphatic substituents as well as cyclic ones. Mechanistic investigations revealed that during catalysis, Ru carboxylate complexes are predominantly formed whereas neither the PNP nor the CN ligand are released from the catalyst in significant amounts.

Regioselective Vinylation of Remote Unactivated C(sp3)?H Bonds: Access to Complex Fluoroalkylated Alkenes

Regioselective incorporation of a particular functional group into aliphatic sites by direct activation of unreactive C?H bonds is of great synthetic value. Despite advances in radical-mediated functionalization of C(sp3)?H bonds by a hydrogen-atom transfer process, the site-selective vinylation of remote C(sp3)?H bonds still remains underexplored. Reported herein is a new protocol for the regioselective vinylation of unactivated C(sp3)?H bonds. The remote C(sp3)?H activation is promoted by a C-centered radical instead of the commonly used N and O radicals. The reaction possesses high product diversity and synthetic efficiency, furnishing a plethora of synthetically valuable E alkenes bearing tri-/di-/mono-fluoromethyl and perfluoroalkyl groups.