350-57-2

Basic information

• Product Name: (1,1,2,2-TETRAFLUOROETHOXY)BENZENE
• Synonyms: (1,1,2,2-Tetrafluoroethoxy)benzene, Phenyl 1,1,2,2-tetrafluoroethyl ether;alpha,alpha,beta,beta-Tetrafluorophenetole 98%;TETRAFLUOROETHOXYBENZENE;(1,1,2,2-tetrafluoroethoxy)-benzen;fentalene-14;(1,1,2,2-TETRAFLUOROETHOXY)BENZENE;TETRAFLUOROETHOXYBENZENE 98%;(1,1,2,2-Tetrafluoroethoxy)benzene98%
• CAS NO: 350-57-2
• Molecular Formula: C₈H₆F₄O
• Molecular Weight: 194.13
• EINECS: 206-505-4
• Product Categories: Oxygen Compounds;Ethers;Organic Building Blocks
• Mol File: 350-57-2.mol

Chemical Properties

• Boiling Point: 152-153 °C(lit.)
• Flash Point: 115 °F
• Appearance: /
• Density: 1.275 g/mL at 25 °C(lit.)
• Vapor Pressure: 4.07mmHg at 25°C
• Refractive Index: n20/D 1.4200(lit.)
• CAS DataBase Reference: (1,1,2,2-TETRAFLUOROETHOXY)BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: (1,1,2,2-TETRAFLUOROETHOXY)BENZENE(350-57-2)
• EPA Substance Registry System: (1,1,2,2-TETRAFLUOROETHOXY)BENZENE(350-57-2)

Safety Data

• Hazard Codes: Xi,T
• Statements: 10-36/37/38
• Safety Statements: 26-36
• RIDADR: UN 1993 3/PG 3
• WGK Germany: 2
• RTECS: DC0340000
• HazardClass: TOXIC
• PackingGroup: III
• Hazardous Substances Data: 350-57-2(Hazardous Substances Data)

Usage

Uses

Used in Polymer Production:
(1,1,2,2-TETRAFLUOROETHOXY)BENZENE is used as a solvent in the polymer industry for its ability to dissolve a wide range of polymers and facilitate their processing. Its non-reactive and non-flammable properties make it an ideal choice for applications that require a safe and stable solvent.
Used in Electronics Manufacturing:
In the electronics industry, (1,1,2,2-TETRAFLUOROETHOXY)BENZENE serves as a solvent for cleaning and degreasing electronic components. Its low volatility and excellent chemical stability ensure that it does not leave residues or cause damage to sensitive electronic parts.
Used in High-Temperature Applications:
Due to its thermal stability, (1,1,2,2-TETRAFLUOROETHOXY)BENZENE is used as a solvent in processes that involve high temperatures. Its ability to maintain its properties under such conditions makes it suitable for applications in the chemical and manufacturing industries where high-temperature environments are common.
Used in Harsh Chemical Environments:
(1,1,2,2-TETRAFLUOROETHOXY)BENZENE is utilized as a solvent in chemical processes that involve harsh or reactive chemicals. Its chemical stability allows it to remain unaffected by these chemicals, ensuring a safe and efficient process.
Overall, (1,1,2,2-TETRAFLUOROETHOXY)BENZENE's versatility, stability, and safety make it a valuable component in various industrial applications, from polymer production to electronics manufacturing and beyond.

InChI:InChI=1/C8H6F4O/c9-7(10)8(11,12)13-6-4-2-1-3-5-6/h1-5,7H

Upstream product

• 116-14-3 polytetrafluoroethylene 
• 108-95-2 phenol 
• 83015-28-5 1,1,2,2-tetrafluoro-1-bromo-2-phenoxyethane 
• 124-73-2 1,2-dibromo-1,1,2,2-tetrafluoroethane 
• 100-67-4 potassium phenolate 

Downstream Products

• 68516-54-1 4-(1,1,2,2-Tetrafluoroethoxy)benzenesulfonyl chloride 
• 1431266-14-6 sodium-4-(1,1,2,2-tetrafluorethoxy)benzenesulfonate 
• 772-53-2 (1,2,2-trifluorovinyloxy)benzene 

Relevant articles and documents

A practical synthesis of aryl tetrafluoroethyl ethers via the improved reaction of phenols with 1,2-dibromotetrafluoroethane

An efficient and practical synthesis of various aryl tetrafluoroethyl ethers by the reaction of phenols with 1,2-dibromotetrafluoroethane and the subsequent reduction with zinc dust was described. The nucleophilic substitution of 1,2-dibromotetrafluoroethane with phenols initiated by bromophilic attack was improved by using Cs2CO3 as a base and DMSO as a solvent.

Nucleophilic difluoroalkylation of benzophenones, benzaldehydes and Schiff's bases by tetrafluoroethyl ether and difluoroacetamide

From gem-difluoromethyl group of 1,1,2,2-tetrafluoroethyl ether and 2,2-difluoroalkylamide, proton can be removed by potassium bis(trimethylsilyl)amide in DMF, THF or toluene. The generated nucleophiles are then condensed with benzophenones, benzaldehydes or Schiff's bases to provide new fluorinated alcohols and amines. Some interesting solvent effects are also observed.

A mild hydrodehalogenation of fluoroalkyl halides

A mild hydrodehalogenation reaction of fluoroalkyl halides (RfCF2X, X = Br, I) has been developed under weakly basic conditions, giving the corresponding hydrogenolysis products with moderate to high yields.

Fluorinated arylethers and methods for use thereof

The invention provides new fluorinated solvents that have many uses. One such use is as a solvent useful in the deposition of organic active materials in the manufacture of organic electronic devices. The new fluorinated solvents are fluorinated arylethers and can be readily prepared from corresponding phenols and fluorinated olefins.

SPONTANEOUS REACTIONS OF POTASSIUM PHENOXIDE WITH DIBROMOPERFLUOROALKANES. FIRST EVIDENCE FOR BROMOPHILIC ATTACK ON C-Br BONDS BY THE PHENOXIDE ION.

In contrast to earlier reports, It has been found that dibromoperfluoroalkanes actually can react spontaneously with PhOK, yielding fluoroalkyl phenyl ethers as products.Evidence for an anionic chain mechanism involving a bromophilic attack by the phenoxyde ion is presented.

CONDENSATION OF 1,2-DIBROMOTETRAFLUOROETHANE WITH VARIOUS POTASSIUM THIOPHENOXIDES AND PHENOXIDES

BrCF2CF2Br reacts easily with various potassium thiophenoxides and phenoxides to give respectively 2-bromo tetrafluoroethyl thioethers and ethers.The lipophilicity of C6H5SCF2CF2Br and C6H5OCF2CF2Br is measured and compared with that of the well known C6H5SCF2CF2H and C6H5OCF2CF2H.