3510-48-3

Basic information

• Product Name: bis(4-chlorobenzylidene)hydrazine
• CAS NO: 3510-48-3
• Molecular Formula: C₁₄H₁₀Cl₂N₂
• Molecular Weight: 277.1486
• Mol File: 3510-48-3.mol
• Article Data: 47

Chemical Properties

• Boiling Point: 368.4°C at 760 mmHg
• Flash Point: 176.6°C
• Density: 1.21g/cm³
• Vapor Pressure: 2.71E-05mmHg at 25°C
• Refractive Index: 1.589
• CAS DataBase Reference: bis(4-chlorobenzylidene)hydrazine(CAS DataBase Reference)
• NIST Chemistry Reference: bis(4-chlorobenzylidene)hydrazine(3510-48-3)
• EPA Substance Registry System: bis(4-chlorobenzylidene)hydrazine(3510-48-3)

Safety Data

• Hazardous Substances Data: 3510-48-3(Hazardous Substances Data)

Upstream product

• 75-27-4 bromodichloromethane 
• 52372-80-2 (4-chlorobenzylidene)hydrazine 
• 354-58-5 1,1,1-Trichloro-2,2,2-trifluoroethane 
• 124-73-2 1,2-dibromo-1,1,2,2-tetrafluoroethane 
• 76-13-1 1,1,2-Trichloro-1,2,2-trifluoroethane 
• 321-14-2 5-chloro-2-hydroxybenzoic acid 
• 62547-34-6 5-chlorosalicylic acid-3-sulfonyl chloride 
• 873-76-7 para-Chlorobenzyl alcohol 
• 19277-54-4 p-chlorophenyldiazomethane 
• 5157-08-4 3-methyl-4,5-dihydro-6-oxopyridazine 
• 104-88-1 4-chlorobenzaldehyde 
• 19350-69-7 4-chlorobenzaldehyde p-toluenesulfonylhydrazone 
• 21540-02-3 3,3'-(hydrazine-1,2-diylidene)bis(indolin-2-one) 
• 70565-01-4 3-(2-(4-methoxybenzylidene)hydrazono)indolin-2-one 

Downstream Products

• 722-32-7 (2-(4-chlorophenyl)methylene)hydrazolyl-1,3-thiazolidin-4-one 
• 904-60-9 4-chloro-benzaldehyde [5-(4-chloro-benzylidene)-4-oxo-thiazolidin-2-ylidene]-hydrazone 
• 111474-68-1 4,4'-Dichlor-benzaldazin-monoxyd 
• 37932-51-7 1,4-dichloro-1,4-bis(4-chlorophenyl)-2,3-diazabutadiene 
• 104-88-1 4-chlorobenzaldehyde 
• 302-01-2 hydrazine 
• 1613288-01-9 C₅₀H₄₄Cl₄N₄O₄P₂ 
• 1374997-37-1 diethyl [(2E)-2-(4-chlorobenzylidene)hydrazino](4-chlorophenyl)methyl phosphonate 
• 907169-67-9 3,7-bis(4-chlorophenyl)-tetrahydro-[1,2,4]triazolo[1,2-a][1,2,4]triazole-1,5-dithione 
• 870080-23-2 3,3-dimethyl-7,11-cis-di(p-chlorophenyl)-2,4-dioxaspiro[5.5]undecane-1,5,9-trione 
• 1166381-83-4 7,14-bis(4-chlorophenyl)-11,11-dimethyl-1,4,10,12-tetraoxadispiro[4.2.5.2]pentadecane-9,13-dione 
• 1189947-88-3 4-chlorophenyl(3,5-xylyl)methane 
• 30203-86-2 4-[(4-chlorophenyl)methyl]biphenyl 

Relevant articles and documents

Reaction of aldehydes with hydrazine in the system sulfur-alkali

Dissolution of sulfur in the system hydrazine hydrate-alkali leads to strong activation of hydrazine, so that the latter readily reacts at room temperature with aldehydes of the aromatic and thiophene series to give the corresponding aldehyde azines in high yield. The mechanism of activating effect of sulfur is discussed.

Dihydrazone compound high in affinity with Abeta protein and Tau protein, derivative thereof, and applications of dihydrazone compound and derivative

The invention provides a dihydrazone compound high in affinity with Abeta protein and Tau protein, a derivative thereof, and applications of the dihydrazone compound and the derivative. The structureof the dihydrazone compound is represented by formula I. The dihydrazone compound can be directly taken as a fluorescence probe used for detecting neurofibrillary tangles in vivo or in tissue samples;when the dihydrazone compound is adopted in nuclear medicine imaging, appropriate radioisotopes are needed for labeling. The dihydrazone compound is especially suitable to be used for diagnosis of neurodegenerative diseases, and diagnosis of patients with diseases with Abeta plaques including Alzheimer's disease.

Mononuclear half-sandwich iridium and rhodium complexes through C?H activation: Synthesis, characterization and catalytic activity

A series of mononuclear half-sandwich cyclometalated group 9 (Ir and Rh) metal complexes were synthesized in good yields through metal-mediated C?H bond activation. These air-stable C, N-chelate mode complexes have similar solid state structures. Both experimental results and DFT calculations confirmed that no binuclear complexes were generated in this reaction. The iridium complex 3a exhibited good catalytic activity for the reduction of both electron-rich and electron-poor aryl imines with low catalyst loading in the presence of formic acid/triethylamine (F/T) azeotropic mixture. All complexes were fully characterized by elemental analysis and IR and NMR spectroscopies. The structures of 1a, 1b, 2a, 3a and 4b (see chemical structure formula in Scheme 1 and Scheme 2) were further confirmed by single-crystal X-ray analysis.