351457-12-0 Usage
Description
1H-INDAZOLE-3-(N-METHOXY-METHYL)CARBAMIDE is a chemical compound characterized by its molecular formula C10H11N3O2. It is a derivative of indazole, a heterocyclic aromatic organic compound, and is specifically classified as an N-methoxy-N-methylcarbamate. 1H-INDAZOLE-3-(N-METHOXY-METHYL)CARBAMIDE is recognized for its potential biological activities and is a valuable target for medicinal chemistry and drug discovery due to its role in the synthesis of pharmaceuticals and biologically active compounds.
Uses
Used in Pharmaceutical Industry:
1H-INDAZOLE-3-(N-METHOXY-METHYL)CARBAMIDE is used as a key intermediate in the synthesis of various pharmaceuticals for its potential to contribute to the development of new drugs. Its unique structure allows it to be a building block in the creation of compounds with specific therapeutic properties.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1H-INDAZOLE-3-(N-METHOXY-METHYL)CARBAMIDE is utilized as a starting material for the design and synthesis of biologically active molecules. Its presence in the molecular structure can influence the pharmacokinetics and pharmacodynamics of the resulting compounds, making it a crucial component in drug discovery processes.
Used in Biological Research:
1H-INDAZOLE-3-(N-METHOXY-METHYL)CARBAMIDE is also used in biological research as a tool to study the mechanisms of action of various biologically active compounds. Its incorporation into different chemical entities can help researchers understand the interactions between these compounds and their biological targets, thus advancing the understanding of disease mechanisms and potential therapeutic interventions.
Check Digit Verification of cas no
The CAS Registry Mumber 351457-12-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,1,4,5 and 7 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 351457-12:
(8*3)+(7*5)+(6*1)+(5*4)+(4*5)+(3*7)+(2*1)+(1*2)=130
130 % 10 = 0
So 351457-12-0 is a valid CAS Registry Number.
351457-12-0Relevant articles and documents
Discovery of novel 4-azaaryl-N-phenylpyrimidin-2-amine derivatives as potent and selective FLT3 inhibitors for acute myeloid leukaemia with FLT3 mutations
Long, Yi,Yu, Mingfeng,Ochnik, Aleksandra M.,Karanjia, Jasmine D.,Basnet, Sunita KC.,Kebede, Alemwork A.,Kou, Lianmeng,Wang, Shudong
, (2021/02/03)
Feline McDonough sarcoma (FMS)-like tyrosine kinase 3 (FLT3) is one of the most pursued targets in the treatment of acute myeloid leukaemia (AML) as its gene amplification and mutations, particularly internal tandem duplication (ITD), contribute to the pa
P2X3 AND/OR P2X2/3 COMPOUNDS AND METHODS
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Paragraph 0271-0274, (2018/04/17)
The present disclosure provides novel compounds and methods for preparing and using these compounds. In one embodiment, the compounds are of the structure of formula (I), wherein R1-R7 are defined herein. In a further embodiment, these compounds are useful in method for regulating one or both of the P2X3 or P2X2/3 receptors. In another embodiment, these compounds are useful for treating pain in patients by administering one or more of the compounds to a patient. In another embodiment, these compounds are useful for treating respiratory dysfunction in patients by administering one or more of the compounds to a patient.
THERAPEUTIC INHIBITORY COMPOUNDS
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Paragraph 00236, (2018/02/22)
Provided herein are heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds. Said heterocyclic derivative compounds are complement factor D inhibitors. Such compounds are useful for treating complement related disorders including, but are not limited to, autoimmune, inflammatory, and neurodegenerative diseases.
