3519-57-1Relevant academic research and scientific papers
Synthesis of α-hydroxyl amides via direct amidation of lactic acid at solvent- and catalyst-free conditions
Huang, Meiying,Zhong, Shanshan,Xu, Mengli,Liu, Yunyun
, p. 274 - 276 (2015/06/02)
The efficient synthesis of α-hydroxy-amides has been achieved by the direct amidation of lactic acid using primary amines. The reactions proceed smoothly under solvent-free conditions without using any catalyst. In general, good to excellent yields of products are obtained.
NEW FACILE SYNTHESIS OF α-HYDROXYAMIDES:INTERMOLECULAR AND INTRAMOLECULAR CATALYSIS IN THE REACTION OF α-HYDROXYCARBOXYLIC ACIDS WITH N-SULFINYLAMINES.
Shin, Jai Moo,Kim, Yong Hae
, p. 1921 - 1924 (2007/10/02)
α-Hydroxycarboxylic acids (1) reacted with N-sulfinylanilines (2) to give the corresponding α-hydroxyanilides (5) in quantitative yields under mild condition: the reaction appears to involve intermolecular catalysis by the carboxylic acid moiety and intra
Reduction of Nitroarenes to Anilines in Basic Alcoholic Media
Prato, Maurizio,Quintily, Ugo,Scorrano, Gianfranco
, p. 1419 - 1424 (2007/10/02)
Substituted nitrobenzenes are reduced by alkoxide ions in alcohols to the corresponding azoxy and aniline derivatives.The reaction leading to anilines has been investigated in detail.Two different processes have been identified, both initiated by the condensation between the nitrosoarene intermediate (the first product of the reduction reaction) and the product of oxidation of the solvent.The imino derivative thus formed (ArN=CH-COR) may either undergo hydrolysis (to aniline) or form, through a series of redox processes, compounds containing the ArNH-CO moiety.These are also hydrolysed to anilines in a slower reaction.
