3551-75-5

Basic information

• Product Name: m-Oxalotoluidide
• Synonyms: m-Oxalotoluidide;N,N'-Bis(3-Methylphenyl)ethanediaMide;N1,N2-Bis(3-Methylphenyl)ethanediaMide
• CAS NO: 3551-75-5
• Molecular Formula: C₁₆H₁₆N₂O₂
• Molecular Weight: 268.31044
• Product Categories: Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 3551-75-5.mol
• Article Data: 8

Chemical Properties

• Melting Point: 135 °C
• Appearance: /
• Density: 1.241±0.06 g/cm3(Predicted)
• PKA: 11.13±0.70(Predicted)
• CAS DataBase Reference: m-Oxalotoluidide(CAS DataBase Reference)
• NIST Chemistry Reference: m-Oxalotoluidide(3551-75-5)
• EPA Substance Registry System: m-Oxalotoluidide(3551-75-5)

Safety Data

• Hazardous Substances Data: 3551-75-5(Hazardous Substances Data)

Upstream product

• 1619-73-4 ethyl 2-oxo-4-phenylbut-3-ynoate 
• 108-44-1 1-amino-3-methylbenzene 
• 79-37-8 oxalyl dichloride 
• 64-19-7 acetic acid 
• 95-92-1 oxalic acid diethyl ester 
• 62134-48-9 N-m-tolylsuccinamic acid 
• 109423-08-7 1,3,5-tris(m-tolyl)perhydro-1,3,5-triazine 

Downstream Products

• 620-50-8 N,N'-di(m-tolyl)urea 
• 1128-47-8 6-methylindoline-2,3-dione 
• 7030-60-6 N,N'-di-m-tolyl-ethylenediamine 
• 401585-34-0 oxalic acid-bis(3-tolylimidoyl)chloride 

Relevant articles and documents

METHOD FOR CONVERTING HYDROXYL GROUP OF ALCOHOL

The present invention relates to: a method for converting a hydroxyl group of an alcohol; and a catalyst which makes the method possible. A method for converting a hydroxyl group of an alcohol according to the present invention is characterized by producing a compound represented by CH(R1)(R2)Nu (wherein R1, R2 and Nu are as defined below) by reacting an alcohol represented by CH(R1)(R2)OH (wherein each of R1 and R2 represents a hydrogen atom, an optionally substituted alkyl group, or the like) and a compound having an active proton, which is represented by H-Nu (wherein Nu represents a group represented by —CHX1-EWG1 or —NR3R4; X1 represents a hydrogen atom or the like; EWG1 represents an electron-withdrawing group; and each of R3 and R4 represents a hydrogen atom, an optionally substituted alkyl group, or the like), with each other in the presence of a complex of a group 7-11 metal of the periodic table and at least one solid base that is selected from the group consisting of layered double hydroxides, composite oxides and calcium hydroxide.

Reagent Design and Ligand Evolution for the Development of a Mild Copper-Catalyzed Hydroxylation Reaction

Parallel synthesis and mass-directed purification of a modular ligand library, high-throughput experimentation, and rational ligand evolution have led to a novel copper catalyst for the synthesis of phenols with a traceless hydroxide surrogate. The mild reaction conditions reported here enable the late-stage synthesis of numerous complex, druglike phenols.

Synthesis of N,N′-diarylalkanediamides and their antimycobacterial and antialgal activity

A set of N,N′-diarylalkanediamides was synthesized. The compounds were tested for their antimycobacterial and antialgal activity. The antimycobacterial activity of N,N′-diarylalkanediamides depends on the lipophilicity of the respective acid. Antimycobacteri-ally active substances were found only in the series of N,N′-diarylethanediamides and N,N′-diarylbutanediamides. Other compounds (derivatives of pentane-, hexane-, octane- and nonanediamide) were inactive against various strains of mycobacteria. The compounds inhibited growth and chlorophyll production in Chlorella vulgaris. Their relatively low antial-gal activity is probably connected with their lowered aqueous solubility, and hence by a restricted passage of the inhibitor through the hydrophilic regions of thylakoid membranes.