35889-87-3

Basic information

• Product Name: 1H-pyrrole-2-carboxylic acid benzyl ester
• Synonyms: 1H-pyrrole-2-carboxylic acid benzyl ester
• CAS NO: 35889-87-3
• Molecular Weight: 201.225
• Mol File: 35889-87-3.mol
• Article Data: 15

Chemical Properties

• Melting Point: 54-55 °C
• Boiling Point: 361.9±17.0 °C(Predicted)
• Density: 1.209±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1H-pyrrole-2-carboxylic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-pyrrole-2-carboxylic acid benzyl ester(35889-87-3)
• EPA Substance Registry System: 1H-pyrrole-2-carboxylic acid benzyl ester(35889-87-3)

Safety Data

• Hazardous Substances Data: 35889-87-3(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 634-97-9 pyrrole-2-carboxyl acid 
• 100-51-6 benzyl alcohol 
• 35302-72-8 pyrrol-2-yl trichloromethyl ketone 
• 20194-18-7 sodium phenyl-methanolate 
• 1003-29-8 2-pyrrole aldehyde 
• 865469-49-4 (S)-2-benzyl 1-tert-butyl 1H-pyrrole-1,2(2H,5H)-dicarboxylate 
• 63366-76-7 (toluene-4-sulfonylamino)acetic acid benzyl ester 
• 882980-43-0 2-benzyloxy-1-methylpyridinium triflate 
• 138163-84-5 3-Hydroxy-1-(toluene-4-sulfonyl)-pyrrolidine-2-carboxylic acid benzyl ester 

Downstream Products

• 183172-57-8 benzyl 5-formyl-1H-pyrrole-2-carboxylate 
• 185621-30-1 1,9-Bis(carbobenzoxy)-5-phenyldipyrromethane 
• 142955-54-2 N-(N',N'-bis-Boc-phenylalanyl)-2-pyrrolecarboxylic acid benzyl ester 

Relevant articles and documents

ARYL SULFONAMIDES AS SMALL MOLECULE STAT3 INHIBITORS

The present disclosure provides pharmaceutical compositions comprising aryl sulfonamide Stat3 small molecule inhibitors and certain pharmaceutically acceptable salts thereof, and methods of their use for treating cancer.

BRANIMYCIN DERIVATIVES AND THEIR USE FOR THE TREATMENT OF BACTERIAL INFECTIOUS DISEASES

A compound is disclosed that has a formula represented by Formula (I). The novel compound of the invention may be prepared as a pharmaceutical composition, and may be useful in the treatment of infectious diseases, in particular bacterial infectious disea

Cooperative N-Heterocyclic Carbene (NHC) and Ruthenium Redox Catalysis: Oxidative Esterification of Aldehydes with Air as the Terminal Oxidant

The paper describes a cooperative NHC (N-heterocyclic carbene) and ruthenium-based redox catalysis for the mild aerobic oxidative esterification of various aromatic and heteroaromatic aldehydes. The ruthenium(II) complex Ru(bpz)3(PF6)2 (bpz=2,2′-bipyrazine) as catalyst is shown to be compatible with free NHCs. The NHC is used in these cascade reactions for the umpolung of the aldehyde to form the corresponding Breslow intermediate which in turn gets oxidized to an acylazolium ion by the ruthenium redox catalyst. Air is used as a terminal oxidant for oxidation (regeneration) of the ruthenium catalyst. In addition, we will show that in the absence of the ruthenium redox catalyst and alcohol, NHC-catalyzed aerobic oxidation of aldehydes delivers the corresponding acids in good to excellent yields. Mechanistic studies and DFT calculations supporting our suggested mechanisms are provided. Copyright