359-49-9

Basic information

• Product Name: 2,3,3,3-TETRAFLUOROPROPANOIC ACID
• Synonyms: RARECHEM AL BO 0676;2H-TETRAFLUOROPROPIONIC ACID;2,3,3,3-TETRAFLUOROPROPANOIC ACID;2,3,3,3-TETRAFLUOROPROPIONIC ACID;2,3,3,3-TETRAFLUOROPROPANOIC ACID 97%;propanoic acid, 2,3,3,3-tetrafluoro-
• CAS NO: 359-49-9
• Molecular Formula: C₃H₂F₄O₂
• Molecular Weight: 146.04
• Mol File: 359-49-9.mol
• Article Data: 3

Chemical Properties

• Melting Point: 28.2 °C
• Boiling Point: 120 °C
• Flash Point: 29.3 °C
• Appearance: /
• Density: 1.538 g/cm³
• Vapor Pressure: 7.79mmHg at 25°C
• Refractive Index: 1.306
• Sensitive: Hygroscopic
• CAS DataBase Reference: 2,3,3,3-TETRAFLUOROPROPANOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,3,3-TETRAFLUOROPROPANOIC ACID(359-49-9)
• EPA Substance Registry System: 2,3,3,3-TETRAFLUOROPROPANOIC ACID(359-49-9)

Safety Data

• Hazard Codes: C,Xi
• Statements: 34
• Safety Statements: 26-36/37/39
• RIDADR: 3265
• HazardClass: IRRITANT, CORROSIVE
• Hazardous Substances Data: 359-49-9(Hazardous Substances Data)

Usage

General Description

2,3,3,3-Tetrafluoropropanoic acid is a chemical compound with the formula C3HF5O2. It is a colorless liquid with a faint odor, and it is primarily used as an intermediate in the production of pharmaceuticals and agrochemicals. 2,3,3,3-TETRAFLUOROPROPANOIC ACID is a fluorinated carboxylic acid, and its main application is as a building block in the synthesis of various fluorinated compounds. It is also used in the production of fluorinated polymers, and it can act as a corrosion inhibitor in certain industrial processes. 2,3,3,3-Tetrafluoropropanoic acid is considered to be relatively stable and non-reactive under normal conditions, and it is handled and stored in a manner consistent with other carboxylic acids.

InChI:InChI=1/C3H2F4O2/c4-1(2(8)9)3(5,6)7/h1H,(H,8,9)

Upstream product

• 27336-23-8 1,1-dibromo-1,2,2,2-tetrafluoroethane 
• 124-38-9 carbon dioxide 
• 85093-76-1 3-hydroheptafluoro-2-butanone 
• 67641-28-5 perfluoroallylfluorosulphate 
• 27825-79-2 1,1,1,2,tetrafluoro-2-fluorocarbonylethansulfinylfluoride 
• 7722-84-1 dihydrogen peroxide 
• 116-15-4 perfluoropropylene 
• 754-20-1 1-bromo-1-chloro-1,2,2,2-tetrafluoro-ethane 

Downstream Products

• 13859-31-9 2-bromo-2,3,3,3-tetrafluoro-propionic acid 

Relevant articles and documents

Perfluoro allyl fluorosulfate (FAFS): A versatile building block for new fluoroallylic compounds

In this study we will present and discuss both the synthesis of CF 2=CFCF2OSO2F (perfluoroallyl fluorosulfate, FAFS), focusing in particular on the important role of C3F 6/SO3 ratio, reaction temperature and boron catalyst/SO3 ratio on FAFS' yield and selectivity, as well as a wide variety of ionic and radical reactions possible with FAFS. We focused our attention on reactions of FAFS with aliphatic and aromatic alcohols, acyl halides, halides, H2O2, ketones and radicals whose synthesis and reaction mechanisms will be presented and discussed. Particular attention will be devoted to the novel diallyl-fluoroalkyl peroxide obtained. Factors such as pKa and Lowry and Pearson's Hard/Soft Acid-Base Theory which determine the selectivity between Addition/Elimination vs. Nucleophilic Substitution reaction mechanisms on FAFS will also be presented and discussed.

3-HYDROPERFLUORO-2-BUTANONE AND ITS REACTIONS

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