360-53-2

Basic information

• Product Name: 1-METHOXY-(PERFLUORO-2-METHYL-1-PROPENE)
• Synonyms: methylperfluoroi;1-Methoxy-1,3,3,3-tetrafluoro-2-(trifluoromethyl)prop-1-ene 97%;1-Methoxy-1,3,3,3-tetrafluoro-2-(trifluoromethyl)prop-1-ene, 1,1,1,3-Tetrafluoro-2-(trifluoromethyl)-4-oxapent-2-ene;Methyl 1,3,3,3-tetrafluoro-2-(trifluoromethyl)prop-1-en-1-yl ether 97%;Methyl1,3,3,3-tetrafluoro-2-(trifluoromethyl)prop-1-en-1-ylether97%;1-Propene,1,3,3,3-tetrafluoro-1-methoxy-2-(trifluoromethyl)-;1,3,3,3-tetrafluoro-1-methoxy-2-(trifluoromethyl)-1-propen;ether,methyl1,3,3,3-tetrafluoro-2-(trifluoromethyl)propenyl
• CAS NO: 360-53-2
• Molecular Formula: C₅H₃F₇O
• Molecular Weight: 212.07
• Mol File: 360-53-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 98 °C
• Flash Point: 14.6°C
• Appearance: /
• Density: 1.508
• Vapor Pressure: 60.3mmHg at 25°C
• Refractive Index: 1.317
• CAS DataBase Reference: 1-METHOXY-(PERFLUORO-2-METHYL-1-PROPENE)(CAS DataBase Reference)
• NIST Chemistry Reference: 1-METHOXY-(PERFLUORO-2-METHYL-1-PROPENE)(360-53-2)
• EPA Substance Registry System: 1-METHOXY-(PERFLUORO-2-METHYL-1-PROPENE)(360-53-2)

Safety Data

• Hazard Codes: T
• Statements: 23/24/25
• Safety Statements: 26-36-45
• RIDADR: 2810
• HazardClass: TOXIC
• Hazardous Substances Data: 360-53-2(Hazardous Substances Data)

Usage

General Description

1-Methoxy-(perfluoro-2-methyl-1-propene) is a chemical compound that is classified as a perfluoroalkyl ether. It is a colorless liquid with a slightly sweet odor and is often used as a solvent or a surfactant in industrial applications. This chemical is highly fluorinated, meaning it contains fluorine atoms, which gives it its unique properties such as chemical inertness, thermal stability, and resistance to combustion. It is also known for its low surface tension and friction properties. However, due to its highly fluorinated nature, it is important to handle this chemical with care and in accordance with safety guidelines to prevent any potential health and environmental risks.

InChI:InChI=1/C5H3F7O/c1-13-3(6)2(4(7,8)9)5(10,11)12/h1H3

Upstream product

• 382-26-3 1,1,1,3,3-pentafluoro-3-methoxy-2-trifluoromethylpropane 
• 382-21-8 perfluoroisobutylene 
• 1067-52-3 tributyltin methoxide 
• 56152-71-7 1-chloro-2-trifluoromethyl-1,3,3,3-tetrafluoro-1-propene 
• 67-56-1 methanol 

Downstream Products

• 163702-08-7 nonafluoroisobutyl methyl ether 
• 564-10-3 3,3,3-trifluoro-2-(trifluoromethyl)propanoic acid 
• 163702-07-6 methyl nonafluorobutyl ether 
• 360-54-3 methyl 2-(trifluoromethyl)-3,3,3-trifluoropropionate 
• 97653-67-3 4,6-Dimethoxy-2-phenyl-5-trifluoromethyl-pyrimidine 
• 382-30-9 1,1,1,3,3,3-Hexafluoro-2-methoxymethyl-propane 
• 593-53-3 Methyl fluoride 
• 684-36-6 perfluoromethacryloyl fluoride 
• 684-22-0 bis(trifluoromethyl)ketene 
• 92983-83-0 2-phenyl-4-fluoro-5-trifluoromethyl-6-methoxypyrimidine 
• 382-26-3 1,1,1,3,3-pentafluoro-3-methoxy-2-trifluoromethylpropane 
• 97653-57-1 2-methyl-4-fluoro-5-trifluoromethyl-6-methoxypyrimidine 
• 1735-87-1 3,3,3-Trifluoro-2-methyl-2-(trifluoromethyl)propanoyl fluoride 

Relevant articles and documents

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Synthesis of 1-aroyl(1-arylsulfonyl)-4-bis(trifluoromethyl)alkyl semicarbazides as potential physiologically active compounds

1,1-Bis(trifluoromethyl)alkyl isocyanates obtained from perfluoroisobutene (PFIB) react with aroyl(arylsulfonyl)hydrazines. Twenty eight prospective biologically active polyfluorinated 1,4-substituted semicarbazides were synthesized. The structure of each

Synthesis and anticancer activity of N-bis(trifluoromethyl)alkyl-N′-thiazolyl and N-bis(trifluoromethyl)alkyl-N′-benzothiazolyl ureas

A number of N-bis(trifluoromethyl)alkyl-N′-thiazolyl and -benzothiazolyl ureas have been synthesized and evaluated for their in vitro antiproliferative activities against the human cancer cell lines at the National Cancer Institute (NCI, USA). The activity was shown for compounds 8a,c and 9a-c. The most sensitive cell lines relative to the tested compounds are: 8c PC-3 (prostate cancer, log GI50 -7.10), 9c SNB-75 (CNS cancer, log GI50 -5.84), 9b UO-31 (renal cancer, log GI50 -5.66), and SR (leukemia, log GI50 -5.44) human cancer cells.

CONVERSION OF METHOXYPERFLUOROISOBUTENE TO α-METHYLHEXAFLUOROISOBUTYRIC ACID FLUORIDE BY A PHASE TRANSFER CATALYST

Methoxyperfluoroisobutene was converted to α-methylhexafluoroisobutyric acid fluoride by a catalytic amount of phase transfer catalyst in quantitative yield.