36121-84-3

Upstream product

• 6869-70-1 16β-acetoxy-14β,15-epoxy-3-oxobufa-4,20,22-trienolide 
• 470-37-1 cinobufagin 
• 6869-66-5 3-oxo-cinobufagin 

Downstream Products

• 99102-41-7 cinobufagin 3-hemiglutarate p-nitrophenyl ester 
• 470-37-1 3α-hydroxycinobufagin 
• 36615-12-0 cinobufagin 3-hemisuccinate 
• 474-53-3 5?[(3S,5R,8R,9S,10S,13S)?3?hydroxy?10,13?di?methyl?2,3,4,5,6,7,8,9,10,11,12,13?dodecahydro?1H?cyclopenta[a]phenanthren?17?yl]?2H?pyran?2?one 
• 1357380-54-1 1alpha-Hydroxycinobufagin 
• 1108-68-5 cinobufotalin 
• 4026-97-5 cinobufagin 3-acetate 
• 36615-12-0 cinobufagin 3-succinate 

Relevant academic research and scientific papers

Probing the stereoselectivity of OleD-catalyzed glycosylation of cardiotonic steroids?

The glycosyltransferase OleD variant as a catalyst for the glycosylation of four pairs of epimers of cardiotonic steroids (CTS) are assessed. The results of this study demonstrated that the OleD-catalyze glycosylation of CTS is significantly influenced by

SYNTHESIS OF 5α-CINOBUFAGIN

Cinobufagin (I) and cinobufotalin (IV) isolated from the Chinese toad venom preparation Ch'an Su were used as starting points for synthesis of 5α-cinobufagin (III) via the 3-oxo-4-ene derivative VII.Lithium borohydride reduction of ketone VII afforded 5α-cinobufagin (III) accompanied by 3-epicinobufagin (IX).Ring A diene II, was obtained as one of the dichlorodicyanobenzoquinone oxidation products of 3-oxocinobufagin (V).