36160-54-0Relevant academic research and scientific papers
Design and synthesis of 7-alkoxy-4-heteroarylamino-3-quinolinecarbonitriles as dual inhibitors of c-Src kinase and nitric oxide synthase
Cao, Xin,You, Qi-Dong,Li, Zhi-Yu,Guo, Qing-Long,Shang, Jing,Yan, Ming,Chern, Ji-Wang,Chen, Men-Ling
, p. 5890 - 5898 (2008/12/21)
Because both c-Src and iNOS are key regulatory enzymes in tumorigenesis, a new series of 4-heteroarylamino-3-quinolinecarbonitriles as potent dual inhibitors of both enzymes were designed, prepared, and evaluated for blocking multiple signaling pathways i
THE NUCLEOPHILIC AROMATIC PHOTOSUBSTITUTION IN PHOTOAFFINITY LABELLING. A MODEL STUDY OF A CYCLOHEXIMIDE DERIVATIVE.
Castello, A.,Marquet, J.,Moreno-Manas, M.,Sirera, X.
, p. 2489 - 2492 (2007/10/02)
The photoreactions of several 4-nitrocatechol ethers with the relatively hard nucleophile methylamine occurs at the meta position respect to the nitro group.A derivative of the antibiotic cycloheximide carrying a 4-nitrocatechol ether moiety reacts with methylamine affording an in vitro model for photoaffinity labelling.
