36247-07-1

Upstream product

• 591-19-5 m-Bromoaniline 
• 98-88-4 benzoyl chloride 
• 591-50-4 iodobenzene 
• 20358-05-8 7-bromo-1,3-benzothiazol-2-amine 
• 10286-85-8 N-(3-bromophenyl)benzamide 
• 65-85-0 benzoic acid 
• 824932-42-5 2-amino-5-bromobenzenethiol 
• 108752-45-0 N-(3-bromophenyl)benzothioamide 

Relevant academic research and scientific papers

Exogenous Photosensitizer-, Metal-, and Base-Free Visible-Light-Promoted C-H Thiolation via Reverse Hydrogen Atom Transfer

Visible-light-driven, intramolecular C(sp2)-H thiolation has been achieved without addition of a photosensitizer, metal catalyst, or base. This reaction induces the cyclization of thiobenzanilides to benzothiazoles. The substrate absorbs visible light, and its excited state undergoes a reverse hydrogen-atom transfer (RHAT) with 2,2,6,6-tetramethylpiperidine N-oxyl to form a sulfur radical. The addition of the sulfur radical to the benzene ring gives an aryl radical, which then rearomatizes to benzothiazole via RHAT.

COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND A ELECTRONIC DEVICE THEREOF

The present invention relates to a novel compound, to an electro-organic device using same, and to an electronic device thereof. According to the present invention, the light-emitting efficiency, the color purity, and the life of a device can be increased

Method for preparing benzothiazole compound through microwave catalysis in water phase

The invention discloses a method for preparing a benzothiazole compound through/under microwave catalysis in a water phase. A water-soluble coordination compound is used as a catalyst, and a reactionof inorganic sulfide, 2-iodoaniline and aldehyde is efficiently catalyzed through microwaves in a pure water phase. The method for preparing the benzothiazole compound is environmentally friendly, convenient to operate, safe, cheap and efficient. Compared with the prior art, the method is applied to a large quantity of functional groups, high in yield, simple to operate, safe, low in cost and environmentally friendly and produces a few byproducts.

Spirofluorene organic electroluminescence compound and organic electroluminescence device

The invention provides a spirofluorene organic electroluminescence compound which has the structure as shown in the specification. The compound has high thermal stability, high luminous efficiency and high luminous purity, can be used for manufacturing organic electroluminescence devices and is applied to the fields of organic solar cells, organic thin-film transistors or organic photoreceptors. The invention further provides an organic electroluminescence device which comprises an anode, a cathode and an organic layer, wherein the organic layer comprises at least one of a luminous layer, a hole injection layer, a hole transport layer, a hole barrier layer, an electron injection and an electron transport layer; at least one layer in the organic layer comprises the compound shown in the structural formula I. The organic electroluminescence device has the advantages of high electroluminescence efficiency, excellent color purity and long service life.

Novel benzothiazole derivatives for differentiation of neural stem cells and use thereof

The present invention relates to novel benzothiazole derivatives for differentiation control of neural stem cells and to use thereof. In the present invention, the novel benzothiazole derivatives which are manufactured by using an organic synthetic method are treated with the neural stem cells, and thus it was confirmed that the differentiation to the neural cells are promoted, thereby being usefully used as a treatment agent for neural cell damage diseases. In a differentiation promoting process to the neural cells, a remarkable increase in secretion of cytokine, such as LIFIL-6, CNTF, and the like was confirmed, thereby being expected to be utilized as reagents for manufacturing the same.COPYRIGHT KIPO 2017

External Oxidant-Free Oxidative Cross-Coupling: A Photoredox Cobalt-Catalyzed Aromatic C-H Thiolation for Constructing C-S Bonds

An external oxidant-free oxidative coupling for aromatic C-H thiolation by visible-light photoredox cobalt-catalysis has been developed. Various substrates could afford benzothiazoles in good to excellent yields, and only H2 is generated as a side product. When catalytic TBAOH was used as the base, not only 2-aryl but also 2-alkylbenzothiazoles could be obtained through this novel dehydrogenative coupling reaction. This method could be scaled up and applied to the synthesis of biologically active molecules bearing benzothiazole structural scaffolds (potent antitumor agents). Furthermore, the unexpected oxidation byproduct amides, which are often generated in oxidative cyclization of thiobenzanilides, can be completely avoided. Mechanistic studies showed that the H2 originates from the substrates. The kinetic studies indicate that the interaction between the cobalt catalyst and proton might be involved in the rate-limiting process. (Chemical Equation Presented).

Aerobic visible-light photoredox radical C-H functionalization: Catalytic synthesis of 2-substituted benzothiazoles

An aerobic visible-light driven photoredox catalytic formation of 2-substituted benzothiazoles through radical cyclization of thioanilides has been accomplished. The reaction features C-H functionalization and C-S bond formation with no direct metal involvement except the sensitizer. The reaction highlights the following: (1) visible-light is the reaction driving force; (2) molecular oxygen is the terminal oxidant, and (3) water is the only byproduct.