362470-63-1

Basic information

• Product Name: (S)-2-(3-Benzoyl-phenyl)-propionic acid (S)-1-carbamoylmethyl-4,4-dimethyl-2-oxo-pyrrolidin-3-yl ester
• Synonyms: (S)-2-(3-Benzoyl-phenyl)-propionic acid (S)-1-carbamoylmethyl-4,4-dimethyl-2-oxo-pyrrolidin-3-yl ester
• CAS NO: 362470-63-1
• Molecular Weight: 422.481
• Mol File: 362470-63-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-(3-Benzoyl-phenyl)-propionic acid (S)-1-carbamoylmethyl-4,4-dimethyl-2-oxo-pyrrolidin-3-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(3-Benzoyl-phenyl)-propionic acid (S)-1-carbamoylmethyl-4,4-dimethyl-2-oxo-pyrrolidin-3-yl ester(362470-63-1)
• EPA Substance Registry System: (S)-2-(3-Benzoyl-phenyl)-propionic acid (S)-1-carbamoylmethyl-4,4-dimethyl-2-oxo-pyrrolidin-3-yl ester(362470-63-1)

Safety Data

• Hazardous Substances Data: 362470-63-1(Hazardous Substances Data)

Upstream product

• 117895-47-3 3-(benzyloxy)-4,4-dimethyldihydrofuran-2(3H)-one 
• 362470-38-0 ((3S)-3-((1S)-4,7,7-trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyloxy)-4,4-dimethyl-2-oxopyrrolidin-3-yl)acetic acid tert-butyl ester 
• 362470-32-4 (RS)-(3-benzyloxy-4,4-dimethyl-2-oxopyrrolidin-1-yl)acetic acid tert-butyl ester 
• 362470-41-5 (S)-(3-hydroxy-4,4-dimethyl-2-oxopyrrolidin-1-yl)acetic acid tert-butyl ester 
• 362470-34-6 (RS)-(3-hydroxy-4,4-dimethyl-2-oxopyrrolidin-1-yl)acetic acid tert-butyl ester 
• 22071-15-4 ketoprofen 
• 59512-44-6 ketoprofen chloride 
• 362470-46-0 (S)-(3-hydroxy-4,4-dimethyl-2-oxopyrrolidin-1-yl)acetic acid 
• 362470-30-2 (+/-)-3-benzyloxy-4,4-dimethylpyrrolidin-2-one 

Downstream Products

• 22161-81-5 S-ketoprofen 
• 56105-81-8 R-ketoprofen 
• 22071-15-4 ketoprofen 

Relevant articles and documents

Synthesis of a new insoluble polymer-supported chiral alcohol auxiliary and its first application to nucleophilic addition to ketenes

The preparation of a new optically active alcohol with a carboxylic function that allowed its attachment to an amine-functionalized insoluble polymer is described. Its first use as a polymer supported chiral auxiliary is demonstrated by asymmetric transformation of two racemic aryl propionic acids via ketene formation (95-96% ee).