362492-00-0

Basic information

• Product Name: 2-BOC-6-HYDROXY-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-1-CARBOXYLIC ACID
• Synonyms: 6-HYDROXY-3,4-DIHYDRO-1H-ISOQUINOLINE-1,2-DICARBOXYLIC ACID 2-TERT-BUTYL ESTER;2-BOC-6-HYDROXY-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-1-CARBOXYLIC ACID;2-BOC-6-HYDROXY-3,4-DIHYDRO-1H-ISOQUINOLINE-1-CARBOXYLIC ACID;2-Boc-6-hydroxy-1,2,3,4-tetrahydro-isoquinoline-1-carboxylicacid362492-00-0;1,2(1H)-Isoquinolinedicarboxylic acid, 3,4-dihydro-6-hydroxy-, 2-(1,1-dimethylethyl) ester;2-[(tert-butoxy)carbonyl]-6-hydroxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid
• CAS NO: 362492-00-0
• Molecular Formula: C₁₅H₁₉NO₅
• Molecular Weight: 293.32
• Mol File: 362492-00-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 497.928 °C at 760 mmHg
• Flash Point: 254.938 °C
• Appearance: /
• Density: 1.303 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.579
• CAS DataBase Reference: 2-BOC-6-HYDROXY-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-1-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BOC-6-HYDROXY-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-1-CARBOXYLIC ACID(362492-00-0)
• EPA Substance Registry System: 2-BOC-6-HYDROXY-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-1-CARBOXYLIC ACID(362492-00-0)

Safety Data

• Hazardous Substances Data: 362492-00-0(Hazardous Substances Data)

Usage

General Description

2-BOC-6-HYDROXY-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-1-CARBOXYLIC ACID is a chemical compound with a molecular formula C16H21NO6. It is a derivative of isoquinoline and belongs to the class of carboxylic acids. The compound contains a BOC (tert-butoxycarbonyl) protecting group on the nitrogen atom and a hydroxy group at the C-6 position of the isoquinoline ring. It is commonly used as a building block in organic synthesis and medicinal chemistry for the preparation of diverse pharmaceuticals and bioactive molecules. 2-BOC-6-HYDROXY-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-1-CARBOXYLIC ACID has potential applications in drug development and research due to its structural versatility and biological activities.

InChI:InChI=1/C15H19NO5/c1-15(2,3)21-14(20)16-7-6-9-8-10(17)4-5-11(9)12(16)13(18)19/h4-5,8,12,17H,6-7H2,1-3H3,(H,18,19)

Upstream product

• 2039-67-0 2-(3-methoxyphenyl)-1-ethanamine 
• 38449-59-1 2-(3-hydroxyphenyl)ethylamine hydrobromide 
• 1068562-72-0 C₂₁H₂₉NO₇ 
• 128073-50-7 ethyl (1SR)-6-hydroxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylate hydrochloride 
• 3458-98-8 3-hydroxyphenylethylamine hydrochloride 
• 128073-49-4 ethyl (1SR)-6-hydroxy-2-(tert-butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxylate 
• 350014-18-5 1,2,3,4-Tetrahydro-6-hydroxy-1-isoquinolinecarboxylic acid methyl ester 
• 91523-50-1 rac-6-hydroxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid 
• 588-05-6 m-tyramine 
• 350014-19-6 methyl N-(tert-butyloxycarbonyl)-6-hydroxy-3,4-dihydro-1H-isoquinoline-1-carboxylate 

Downstream Products

• 531554-36-6 C₂₈H₃₉N₃O₃ 
• 373638-24-5 C₂₉H₄₁N₃O₄ 
• 373637-08-2 C₂₉H₄₁N₃O₄ 
• 531553-76-1 C₃₅H₃₇N₃O₃ 
• 499139-27-4 2-(tert-butoxycarbonyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid 
• 1068527-08-1 C₂₆H₂₅NO₄ 
• 531556-15-7 C₂₄H₂₃NO₃*ClH 

Relevant articles and documents

Heterocyclic compound

The present invention relates to compound (I) or a salt thereof which has a ROR γ t inhibitory action. wherein each symbol is as defined in the specification.

Tetrahydroisoquinoline analogs as modulators of chemokine receptor activity

Tetrahydroisoquinoline analogs are provided which are modulators of chemokine receptor activity. The tetrahdroisoquinoline analogs thereof have the structure wherein R1, R2, R3, R3a, X1, X2, X3, X4, m, n and p are as described herein.