36298-55-2

Upstream product

• 620-80-4 ethyl 2-benzylidene acetoacetate 
• 68708-10-1 2-(1-hydroxyimino-ethyl)-3-phenyl-acrylic acid 
• 932-90-1 syn-benzaldehyde oxime 
• 141-97-9 ethyl acetoacetate 
• 5435-44-9 (E)-3-Ureido-but-2-enoic acid ethyl ester 
• 100-52-7 benzaldehyde 
• 932-90-1 Benzaldoxime 
• 4341-76-8 Ethyl 2-butynoate 
• 86119-84-8 phosphoric acid 
• 64-17-5 ethanol 
• 7647-01-0 hydrogenchloride 
• 1517-96-0 3-methyl-5-isoxazolone 
• 5470-11-1 hydroxylamine hydrochloride 
• 105-45-3 acetoacetic acid methyl ester 

Downstream Products

• 353285-56-0 4-(4-bromo-anilinomethylene)-3-methyl-4H-isoxazol-5-one 
• 17975-46-1 3-methyl-4-(4-methoxyphenyl)methyleneisoxazole-5(4H)-one 
• 40538-65-6 3-methyl-4-<(phenylamino)methylene>isoxazol-5(4H)-one 
• 538-51-2 benzylidene phenylamine 
• 128156-37-6 3,3'-dimethyl-2H,2'H-4,4'-benzylidene-bis-isoxazol-5-one 
• 91957-31-2 3-methyl-4-(1-phenyl-propyl)-2H-isoxazol-5-one 
• 112532-09-9 4-(aminophenylmethylene)-3-methylisoxazol-5(4H)-one 
• 93315-83-4 4-benzhydryl-3-methyl-2H-isoxazol-5-one 
• 16430-11-8 [(3-methyl-5-oxo-2,5-dihydro-isoxazol-4-yl)-phenyl-methyl]-phosphonic acid dimethyl ester 
• 2292-43-5 9-methyl-3,4-diphenyl-1,7-dioxa-2,8-diaza-spiro[4.4]nona-2,8-dien-6-one 
• 94005-25-1 4-(4-methoxy-benzhydryl)-3-methyl-2H-isoxazol-5-one 
• 95275-83-5 3-methyl-4-(4-methyl-benzhydryl)-2H-isoxazol-5-one 
• 16430-10-7 [(2,3-dimethyl-5-oxo-2,5-dihydro-isoxazol-4-yl)-phenyl-methyl]-phosphonic acid dimethyl ester 
• 4525-06-8 3''-methyl-3'-phenyl-dispiro[fluorene-9,1'-cyclopropane-2',4''-isoxazol]-5''-one 

Relevant academic research and scientific papers

Fruit Extract of Averrhoa bilimbi: A Green Neoteric Micellar Medium for Isoxazole and Biginelli-Like Synthesis

A transition metal/ligand/additive/promoter-free synthesis of 3-methyl-4-arylmethylene-isoxazol-5(4H)-ones and the Biginelli-like synthesis is carried out in a natural acidic medium of Averrhoa bilimbi extract (ABE) with cleaner and facile approach smenti

A simple and efficient protocol for the synthesis of 3,4-disubstituted isoxazol-5(4h)-ones catalyzed by succinic acid using water as green reaction medium

A simple and efficient protocol has been established to the synthesis of 3,4-disubstituted isoxazol-5(4H)-ones via Knoevenagel condensation reaction. In this synthesis, succinic acid was used as an inexpensive catalyst and water as a green reaction medium

An efficient solvent-free synthesis of 3,4-disubstituted isoxazole-5(4H)-ones using microwave irradiation

I have reported one-pot and three-component synthesis of 3-mehyl-4-arylmethyleneisoxazol-5(4H)-ones using microwave radiation under the solvent-free conditions, in the presence of potassium bromide as the catalyst. The method has given the products in hig

Synthetic enzyme-catalyzed multicomponent reaction for Isoxazol-5(4H)-one Syntheses, their properties and biological application; why should one study mechanisms?

In this work, we describe the application of a synthetic enzyme (synzyme) as the catalyst to promote the multicomponent synthesis of isoxazol-5(4H)-one derivatives. The catalytic system could be used up to 15 times without any notable loss of its activity

One-pot three-component synthesis of isoxazole using ZSM-5 as a heterogeneous catalyst

A mild and convenient route for the synthesis of isoxazole derivatives has been developed using ZSM-5 as a heterogeneous catalyst. The reaction was carried out under a solvent-free condition to afford the desired products in good yields. A variety of func

An improved protocol for the synthesis of 3,4-disubstituted isoxazol-5(4H)-ones through L-valine-mediated domino three-component strategy

Abstract: An expeditious, metal-free protocol has been demonstrated for the synthesis of isoxazolone derivatives using domino multi-component strategy. The envisaged methodology involves the L-valine promoted three-component cyclo-condensation reaction of

Green synthesis of 3,4-disubstituted isoxazol-5(4H)-ones using ZnO@Fe3O4 core–shell nanocatalyst in water

An effective and environmentally benign methodology for the synthesis of isoxazol-5(4H)-one derivatives has been developed using a ZnO@Fe3O4 core–shell nanocatalytic system. The one-pot, multicomponent reaction of an aromatic/heteroc

Cu/TCH-pr&at;SBA-15 nano-composite: A new organometallic catalyst for facile three-component synthesis of 4-arylidene-isoxazolidinones

A copper complex supported on SBA-15 nanoparticles (Cu/TCH-pr&at;SBA-15) was synthesized by the post-synthesis modification of nano-mesoporous silica with 3-chloropropyltriethoxysilane (CPTES) and thiocarbohydrazide (TCH) and subsequent metal-ligand coord

Enantioselective Synthesis of Functionalized Diazaspirocycles from 4-Benzylideneisoxazol-5(4H)-one Derivatives and Isocyanoacetate Esters

Enantioenriched spirocyclic compounds bearing three contiguous stereocenters and high functionalization were obtained through a formal [3+2] cycloaddition reaction catalyzed by a cooperative system. The spiro compounds were synthesized from 4-arylideneisoxazol-5-ones and isocyanoacetate esters using a bifunctional squaramide/Br?nsted base organocatalyst derived from a Cinchona alkaloid and silver oxide as Lewis acid. This method afforded two out of the four possible diastereomers with good yields and high enantiomeric excess for both diastereomers. (Figure presented.).