36413-60-2

Usage

Uses

Used in Pharmaceutical Industry:
1,3,4,5-tetrahydroxycyclohexanecarboxylic acid is used as an intermediate in the production of various pharmaceuticals for its ability to be a key component in the synthesis of antiviral and anticancer drugs, contributing to the development of novel therapeutic agents.
Used in Organic Chemistry:
1,3,4,5-tetrahydroxycyclohexanecarboxylic acid is used as a synthetic building block in organic chemistry due to its versatile structure that allows for the creation of a wide range of natural products and other chemical compounds.
Used in Biomedical Applications:
1,3,4,5-tetrahydroxycyclohexanecarboxylic acid is being studied for use in drug delivery systems to enhance the efficacy and targeted delivery of pharmaceutical agents, potentially improving treatment outcomes.
Additionally, it is considered for use as a chelating agent for metal ions in biomedical applications, which may have implications for detoxification processes or the development of new contrast agents for medical imaging.

Upstream product

• 1049703-62-9 chlorogenic acid 
• 640-06-2 1,3,4-trihydroxy-6-oxa-bicyclo[3.2.1]octan-7-one 
• 202650-88-2 3-caffeoylquinic acid 
• 7647-01-0 hydrogenchloride 
• 7664-93-9 sulfuric acid 
• 7732-18-5 water 
• 144-62-7 oxalic acid 
• 25514-46-9 (1S,3S,4R,5R)-3-((3-(3,4-dihydroxyphenyl)propanoyl)oxy)-1,4,5-trihydroxycyclohexane-1-carboxylic acid 
• 77-95-2 D-(-)-quinic acid 
• 191916-39-9 methyl (-)-quinate 
• 135711-62-5 methyl quinicate 
• 213250-58-9 (3R,5R)-3,5-bis[(tert-butyldimethylsilyl)oxy]-1-hydroxy-4-oxocyclohexanecarboxylic acid methyl ester 
• 896-60-6 (+/-)-1,3t,4t-triacetoxy-5c-hydroxy-cyclohexane-r-carboxylic acid-lactone 
• 770-67-2 (+/-)-γ-Quinide 

Downstream Products

• 99-50-3 3,4-Dihydroxybenzoic acid 
• 1768-31-6 pentachloroacetone 
• 81010-88-0 2,5-dihydroxy-benzene-1,3-disulfonic acid 
• 618-46-2 m-Chlorobenzoyl chloride 
• 90-02-8 salicylaldehyde 
• 123-31-9 hydroquinone 
• 65-85-0 benzoic acid 
• 106-51-4 p-benzoquinone 
• 71-43-2 benzene 
• 99-96-7 4-hydroxy-benzoic acid 
• 32469-24-2 (1R,3R,4R,5R)-(-)-quinic acid tetraacetate 
• 14210-97-0 1,4-dibenzoyloxybenzene 
• 126-47-6 (-)-quinic acid ; salt with urea 
• 14833-58-0 (3R)-1,3r,4t,5t-tetramethoxy-cyclohexane-c-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Synthesis, Structure, and Tandem Mass Spectrometric Characterization of the Diastereomers of Quinic Acid

(-)-Quinic acid possess eight possible stereoisomers, which occur both naturally and as products of thermal food processing. In this contribution, we have selectively synthesized four isomers, namely, epi-quinic acid, muco-quinic acid, cis-quinic acid, and scyllo-quinic acid, to develop a tandem LC-MS method identifying all stereoisomeric quinic acids. Four derivatives have been unambiguously characterized by single-crystal X-ray crystallography. The missing diastereomers of quinic acid were obtained by nonselective isomerization of (-)-quinic acid using acetic acid/concentrated H2SO4 allowing chromatographic separation and assignment of all diastereomers of quinic acid. We report for the first time that a full set of stereoisomers are reliably distinguishable on the basis of their tandem mass spectrometric fragment spectra as well as their elution order. A rationale for characteristic fragmentation mechanisms is proposed. In this study, we also observed that muco-quinic acid, scyllo-quinic acid, and epi-quinic acid are present in hydrolyzed Guatemalan roasted coffee sample as possible products of roasting.