36600-75-6

Basic information

• Product Name: 2-(4-methoxy-benzyl)-3-oxo-butyric acid ethyl ester
• Synonyms: 2-(4-methoxy-benzyl)-3-oxo-butyric acid ethyl ester
• CAS NO: 36600-75-6
• Molecular Weight: 250.295
• Mol File: 36600-75-6.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: 2-(4-methoxy-benzyl)-3-oxo-butyric acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-methoxy-benzyl)-3-oxo-butyric acid ethyl ester(36600-75-6)
• EPA Substance Registry System: 2-(4-methoxy-benzyl)-3-oxo-butyric acid ethyl ester(36600-75-6)

Safety Data

• Hazardous Substances Data: 36600-75-6(Hazardous Substances Data)

Usage

Ethyl ester derivative

2-(4-methoxy-benzyl)-3-oxo-butyric acid This compound is derived from 2-(4-methoxy-benzyl)-3-oxo-butyric acid by attaching an ethyl ester group.

Common use

Organic synthesis and pharmaceutical research It is widely used as a building block in the synthesis of various pharmaceuticals and bioactive compounds.

Physical appearance

Pale yellow liquid The compound is a pale yellow liquid in its pure form.

Odor

Fruity It has a distinct fruity smell.

Solubility

Insoluble in water, soluble in organic solvents The compound does not dissolve in water but dissolves in organic solvents such as ethanol and ether.

Application

Fragrances and flavorings It is also utilized in the production of fragrances and flavorings for various products.

Hazard classification

Not highly hazardous 2-(4-methoxy-benzyl)-3-oxo-butyric acid ethyl ester is not considered to be a highly hazardous substance.

Safety precautions

Proper handling and storage To prevent potential health or environmental risks, it is important to follow proper handling and storage procedures when working with this compound.

Upstream product

• 2746-25-0 p-Methoxybenzyl bromide 
• 1007476-32-5 sodium ethyl acetylacetate enolate 
• 71-43-2 benzene 
• 824-94-2 p-methoxybenzyl chloride 
• 141-97-9 ethyl acetoacetate 
• 123-11-5 4-methoxy-benzaldehyde 
• 6674-22-2 1,8-diazabicyclo[5.4.0]undec-7-ene 
• 24405-45-6 ethyl 2-(4-methoxybenzylidene)-3-oxobutanoate 
• 6186-89-6 ethyl methyl malonate 
• 104-21-2 p-methoxybenzyl acetate 
• 105-13-5 4-Methoxybenzyl alcohol 

Downstream Products

• 104-20-1 4-(4-methoxyphenyl)-2-butanone 
• 16682-59-0 2-amino-5-(4-methoxy-benzyl)-6-methyl-3H-pyrimidin-4-one 
• 52252-58-1 2-(4-Hydroxybenzyl)acetessigsaeure-ethylester 
• 960312-07-6 ethyl [3-(4-methoxybenzyl)-4,7-dimethyl-2-oxo-2H-chromen-5-yloxy]acetate 
• 219554-67-3 ethyl 2-bromo-3-(4-methoxyphenyl)propionate 
• 27032-79-7 5-(4-Methoxybenzyl)-2,6-dimethyl-3H-pyrimidin-4-one 
• 101793-21-9 4-(4-methoxybenzyl)-3-methyl-1-phenyl-4,5-dihydro-1H-pyrazol-5-one 
• 1453097-35-2 C₁₉H₁₈N₄O₂ 
• 1453097-38-5 C₂₀H₂₀N₄O₂ 

Relevant articles and documents

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Discovery of remogliflozin etabonate: A potent and highly selective SGLT2 inhibitor

We optimized the structure of an active metabolite (1) of WAY-123783, which was obtained from mouse urine after oral administration, to improve selectivity for SGLT2 and oral bioavailability. O-glucoside derivative 24 (remogliflozin etabonate) was subsequently identified as a potent, highly selective, and orally available SGLT2 inhibitor.

Preparation method of 4-p-hydroxyphenyl-2-butanone

The invention discloses a preparation method of 4-p-hydroxyphenyl-2-butanone. The preparation method comprises the following steps of using anisaldehyde from a natural source as a raw material, preparing to obtain anisalcohol through a reduction reaction, preparing to obtain p-methoxybenzyl chloride through a chlorination reaction, next preparing to obtain 2-acetyl-3-(4-methoxyphenyl)ethyl propionate through a substitution reaction with ethyl acetoacetate from a biomass source, next preparing to obtain 4-(4-methoxyphenyl)-2-butanone through hydrolysis and decarboxylation reactions, and finallypreparing to obtain the 4-p-hydroxyphenyl-2-butanone through a demethylation reaction. The preparation method can be used for realizing the preparation of all-natural carbon-source raspberry ketone,and has the advantages of being simple and direct in route, easy to operate, environmentally friendly and high in yield and the like.