367-28-2

Usage

Uses

Used in Organic Synthesis:
2-Fluoro-1,4-benzoquinone is used as a reagent in the synthesis of various organic compounds. Its unique structure and properties make it a valuable component in the creation of new chemical entities.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 2-Fluoro-1,4-benzoquinone serves as an intermediate in the production of various drugs. Its role in the synthesis process is crucial for the development of new medications.
Used in Chemical Industry:
2-Fluoro-1,4-benzoquinone is an important chemical in the field of organic chemistry, with several practical applications in the chemical industry. Its versatility and stability contribute to its widespread use in various chemical processes.
It is important to handle 2-Fluoro-1,4-benzoquinone with caution due to its potential to cause irritation to the skin, eyes, and respiratory system. Proper safety measures should be taken during its use to minimize any adverse effects.

InChI:InChI=1/C6H3FO2/c7-5-3-4(8)1-2-6(5)9/h1-3H

Upstream product

• 55660-73-6 2-fluoro-1,4-hydroquinone 
• 326-18-1 3-fluoro-4-phenylazo-phenol 
• 462-06-6 fluorobenzene 
• 394-41-2 3-fluoro-4-nitrophenol 
• 372-20-3 3-fluorophenol 
• 367-12-4 2-fluorophenol 

Downstream Products

• 82830-49-7 2-fluoro-1,4-dimethoxybenzene 
• 1448799-04-9 (E)-1-(6-fluoro-5-hydroxybenzofuran-3-yl)-3-(4-methoxyphenyl)prop-2-en-1-one 
• 1448799-03-8 (E)-3-(3-chlorophenyl)-1-(6-fluoro-5-hydroxybenzofuran-3-yl)prop-2-en-1-one 
• 82830-48-6 2,5-dimethoxy-4-fluorobenzaldehyde 
• 125903-69-7 (+/-)-DOF 

Relevant academic research and scientific papers

Electron Transfer Oxidation of Benzene and Aerobic Oxidation to Phenol

The activation of very strong C-H bonds, such as those found in benzene, is important also in the quest for new routes for its functionalization. Using the H5PV2Mo10O40 polyoxometalate as an electron transfer oxidant in >50% aqueous H2SO4 as solvent, the formation of a benzene radicaloid species at RT as probed by visible spectroscopy and by EPR spectroscopy recorded at X-band and W-band, including ELDOR-detected NMR, was verified. The viability of the ET oxidation of benzene is supported by DFT calculations, showing the reaction to be exergonic under these conditions. Furthermore, we show that in the presence of O2, very selective hydroxylation to phenol took place.

Reactivity of a Ru(iii)-hydroxo complex in substrate oxidation in water

A mononuclear RuIII-OH complex oxidizes substrates such as hydroquinones in water through a pre-equilibrium process based on adduct formation by hydrogen bonding between the RuIII-OH complex and the substrates. The reaction mechanism switches from hydrogen atom transfer to electron transfer depending on the oxidation potential of substrates. This journal is

Chemical consequences of fluorine substitution. Part 4. Diels-Alder reactions of fluorinated p-benzoquinones with Dane's diene. Synthesis of fluorinated D-homosteroids

Four fluorinated p-benzoquinones (2) have been reacted with Dane's diene (1) in Diels-Alder reactions and the formed fluorinated D-homosteroids were characterized. The number of products, their stereochemistry and stability depends on the fluorine substitution pattern of the corresponding fluorinated p-benzoquinones. If the p-benzoquinone (2) contains an unfluorinated double bond, this bond reacts faster with diene 1 yielding endo-products selectively. In contrast, [4+2]cycloadditions with 2,6-difluoro (2c) and 2,3,5,6-tetrafluorobenzoquinone (2d) gave the products with exo-orientation of the carbonyl part preferably.