36724-16-0

Basic information

• Product Name: Benzofuran, 2-(methylthio)-
• Synonyms: Benzofuran, 2-(methylthio)-
• CAS NO: 36724-16-0
• Molecular Formula: C₉H₈OS
• Molecular Weight: 0
• Mol File: 36724-16-0.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzofuran, 2-(methylthio)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzofuran, 2-(methylthio)-(36724-16-0)
• EPA Substance Registry System: Benzofuran, 2-(methylthio)-(36724-16-0)

Safety Data

• Hazardous Substances Data: 36724-16-0(Hazardous Substances Data)

Upstream product

• 54008-77-4 2-bromo-1-benzofuran 
• 624-92-0 Dimethyldisulphide 
• 69626-75-1 2-iodobenzofuran 
• 271-89-6 1-benzofurane 
• 51534-42-0 1-methylsulfanyl-1-methylsulfinylethylene 
• 108-95-2 phenol 
• 59834-04-7 [1-(2-hydroxy-phenyl)-ethylidene]-carbazic acid ethyl ester 
• 59834-04-7 N'-[1-(2-hydroxy-phenyl)-ethylidene]-hydrazinecarboxylic acid ethyl ester 
• 118-93-4 o-hydroxyacetophenone 
• 59834-06-9 4-(2'-hydroxyphenyl)-1,2,3-thiadiazole 
• 74-88-4 methyl iodide 

Downstream Products

• 4265-27-4 2-n-butylbenzo[b]furan 
• 29909-72-6 3-Phenylbenzofuran 
• 1231219-34-3 2-(benzo[b]thiophen-2-yl)benzofuran 
• 65689-53-4 2,2'-bibenzo[b]thiophene 
• 144499-30-9 S-Methyl 2-(o-hydroxyphenyl)thioethanoate 
• 614-75-5 2-Hydroxyphenylacetic acid 

Relevant articles and documents

Palladium-Catalyzed Arylthiolation of Alkynes Enabled by Surmounting Competitive Dimerization of Alkynes

By overcoming the unwanted catalytic dimerization of terminal alkynes, palladium-catalyzed carbothiolation of alkynes with heteroaryl sulfides has been accomplished to provide the corresponding β-heteroaryl alkenyl sulfides with high regio- and stereosele

Palladium-catalyzed homo-coupling of heteroarylsulfoniums via borylation/Suzuki-Miyaura coupling sequence

Palladium-catalyzed homo-coupling of heteroaryldimethylsulfoniums proceeds in the presence of bis(pinacolato)diboron and a base to yield biheteroaryls. The homo-coupling involves palladium-catalyzed borylation and the subsequent Suzuki-Miyaura coupling. As the sulfoniums were able to be prepared in situ from the corresponding heteroaryl sulfides and methyl triflate, one-pot transformations of heteroaryl sulfides into the homo-coupling products were executed. Furthermore, a facile synthesis of a highly substituted 2,2'-bibenzofuran was accomplished with a combination of Pummerer-type synthesis of 2-benzofuryl sulfide and the present homo-coupling.

Nickel-NHC-catalyzed cross-coupling of 2-methylsulfanylbenzofurans with alkyl grignard reagents

NiCl2(PPh3)(IPr) catalyzes cross-coupling reactions of 2-methylsulfanylbenzofurans with alkyl Grignard reagents. Other nickel complexes such as NiCl2(dppe) failed to catalyze the same reaction. The alkylation is applicable to the synthesis of a couple of protein tyrosine phosphatase inhibitors, 3-(4-biphenylyl)-2-alkylbenzofurans.